International consensus recommendations for the use of prolonged‐infusion beta‐lactam antibiotics: Endorsed by the American College of Clinical Pharmacy, British …
Intravenous β‐lactam antibiotics remain a cornerstone in the management of bacterial
infections due to their broad spectrum of activity and excellent tolerability. β‐lactams are well …
infections due to their broad spectrum of activity and excellent tolerability. β‐lactams are well …
Comprehensive guidance for antibiotic dosing in obese adults
L Meng, E Mui, MK Holubar… - … : The Journal of Human …, 2017 - Wiley Online Library
Physiologic alterations seen in obesity commonly impact the pharmacokinetics (PK) and
pharmacodynamics (PD) of antibiotics and may result in suboptimal dosing in this …
pharmacodynamics (PD) of antibiotics and may result in suboptimal dosing in this …
The pharmacodynamics of prolonged infusion β-lactams for the treatment of Pseudomonas aeruginosa infections: a systematic review
AK Thabit, ALV Hobbs, OE Guzman, KM Shea - Clinical Therapeutics, 2019 - Elsevier
Purpose Pseudomonas aeruginosa is a commonly isolated nosocomial pathogen for which
treatment options are often limited for multidrug-resistant isolates. In addition to newer …
treatment options are often limited for multidrug-resistant isolates. In addition to newer …
Pharmacokinetics and pharmacodynamics of linezolid in plasma/cerebrospinal fluid in patients with cerebral hemorrhage after lateral ventricular drainage by Monte …
X Wu, Y Tang, X Zhang, C Wu… - Drug Design, Development …, 2018 - Taylor & Francis
Objective We investigated the pharmacokinetic (PK) and pharmacodynamic (PD)
parameters of linezolid in patients who had suffered cerebral hemorrhage after lateral …
parameters of linezolid in patients who had suffered cerebral hemorrhage after lateral …
Pharmacokinetic/pharmacodynamic analysis of meropenem for the treatment of nosocomial pneumonia in intracerebral hemorrhage patients by Monte Carlo …
L Kong, Y Tang, X Zhang, G Lu, M Yu… - Annals of …, 2017 - journals.sagepub.com
Background: Nosocomial pneumonia (NP) is a frequent complication among patients with
intracerebral hemorrhage (ICH). However, there are currently no pharmacokinetic (PK) and …
intracerebral hemorrhage (ICH). However, there are currently no pharmacokinetic (PK) and …
Pharmacokinetics and Safety of Doripenem in Healthy Chinese Subjects and Monte Carlo Dosing Simulations
Y Wang, X Liu, K Li, Y Fan, J Yu, H Wu, Y Li, X Wu… - Antibiotics, 2022 - mdpi.com
The aim of this study was to investigate the pharmacokinetics (PK) of doripenem in healthy
Chinese subjects and evaluate the optimal dosage regimens of doripenem. A randomized …
Chinese subjects and evaluate the optimal dosage regimens of doripenem. A randomized …
Pharmacokinetics of doripenem in healthy Koreans and Monte Carlo simulations to explore optimal dosage regimens in patients with normal and enhanced renal …
SW Kim, S Choe, DJ Kim, DY Zang… - Therapeutic Drug …, 2018 - journals.lww.com
Background: Dose adjustment is often required in patients with normal or enhanced renal
function. The aim of this study is to investigate the pharmacokinetic (PK) properties of …
function. The aim of this study is to investigate the pharmacokinetic (PK) properties of …
[PDF][PDF] Lisa T. Hong| Kevin J. Downes 2| Alireza FakhriRavari| Jacinda C. Abdul-Mutakabbir| Joseph L. Kuti 4| Sarah Jorgensen 5| David C. Young 6| Mohammad H …
JA Roberts, T Tängdén, A Zuppa, MH Scheetz - 2023 - researchgate.net
Intravenous β-lactam antibiotics remain a cornerstone in the management of bacterial
infections due to their broad spectrum of activity and excellent tolerability. β-lactams are well …
infections due to their broad spectrum of activity and excellent tolerability. β-lactams are well …
Дозирование антибиотиков при ожирении: размер имеет значение?
ИВ Андреева, ОУ Стецюк… - Клиническая …, 2017 - cyberleninka.ru
В настоящее время в развитых странах ожирением страдают от 15 до 50% населения.
Пациенты с ожирением имеют более высокий риск возникновения инфекций, у них …
Пациенты с ожирением имеют более высокий риск возникновения инфекций, у них …
[PDF][PDF] Pharmacokinetic/pharmacodynamic analysis of meropenem, by Monte Carlo simulation, in both plasma and cerebrospinal fluid in patients with cerebral …
L Kong, H Xu, C Wu, X Kong, M Yu… - International Journal of …, 2020 - researchgate.net
Objective: Patients with cerebral hemorrhage are often prone to intracranial infection, and
meropenem is recommended for treatment. But whether the widely used dosing regimen (1 …
meropenem is recommended for treatment. But whether the widely used dosing regimen (1 …