Biomaterial-based osteoimmunomodulatory strategies via the TLR4-NF-κB signaling pathway: a review

H Xing, R Li, B Ying, Y Qin - Applied Materials Today, 2021 - Elsevier
Osteoimmunomodulation (OIM) has revealed an important role for immune cells in
regulating osseointegration. Biomaterials for OIM have contributed to the evaluation of …

Molecular biomarkers in Perthes disease: A review

V Spasovski, S Srzentić Dražilov, G Nikčević… - Diagnostics, 2023 - mdpi.com
Background: Perthes disease is a juvenile form of osteonecrosis of the femoral head that
affects children under the age of 15. One hundred years after its discovery, some light has …

Ipriflavone-loaded mesoporous nanospheres with potential applications for periodontal treatment

L Casarrubios, N Gómez-Cerezo, MJ Feito… - Nanomaterials, 2020 - mdpi.com
The incorporation and effects of hollow mesoporous nanospheres in the system SiO2–CaO
(nanoMBGs) containing ipriflavone (IP), a synthetic isoflavone that prevents osteoporosis …

Anti‐Interleukin‐6 therapy decreases hip synovitis and bone resorption and increases bone formation following ischemic osteonecrosis of the femoral head

Y Ren, Z Deng, V Gokani, M Kutschke… - Journal of Bone and …, 2020 - academic.oup.com
ABSTRACT Legg‐Calvé‐Perthes disease (LCPD) is a juvenile form of ischemic femoral
head osteonecrosis, which produces chronic hip synovitis, permanent femoral head …

[HTML][HTML] IL6 receptor blockade preserves articular cartilage and increases bone volume following ischemic osteonecrosis in immature mice

N Kamiya, G Kuroyanagi, O Aruwajoye… - Osteoarthritis and …, 2019 - Elsevier
Objective Juvenile ischemic osteonecrosis (JIO) of the femoral head is one of the most
serious hip disorders causing a permanent deformity of the femoral head in childhood. We …

MicroRNA sequence analysis of plasma exosomes in early Legg–Calvé–Perthes disease

Q Huang, B Li, C Lin, X Chen, T Wang, J Liu, Y Liu… - Cellular …, 2022 - Elsevier
Abstract The pathogenesis of Legg–Calvé–Perthes disease (LCPD) has not been fully
elucidated, and studies on epigenetic changes that may contribute to the pathogenesis of …

Inflammatory profile and osteogenic potential of fracture haematoma in humans

I Pountos, G Walters, M Panteli, TA Einhorn… - Journal of clinical …, 2019 - mdpi.com
Fracture haematoma forms immediately after fracture and is considered essential for the
bone healing process. Its molecular composition has been briefly investigated with our …

FSTL1 Promotes Inflammatory Reaction and Cartilage Catabolism through Interplay with NFκB Signaling Pathways in an In Vitro ONFH Model

Y Qu, Y Liu, R Li - Inflammation, 2019 - Springer
Osteonecrosis of the femoral head (ONFH) usually occurs in young people and is closely
associated with autoimmune reactions. Follistatin-like 1 (FSTL1) was recently proven to …

Uncoupled bone remodeling is characteristic of bone damage in premenopausal women with new-onset systemic lupus erythematosus

L Zhu, J Zhang, J Wang, X Lv, D Pu, Y Wang, Q Men… - Lupus, 2021 - journals.sagepub.com
Objective To investigate the mechanism underlying systemic lupus erythematosus (SLE)-
related bone loss by evaluating the bone mineral density (BMD) and bone turnover markers …

T cell protein tyrosine phosphatase in osteoimmunology

Y Wang, S Liu, T Jia, Y Feng, W Zhang, X Xu… - Frontiers in …, 2021 - frontiersin.org
Osteoimmunology highlights the two-way communication between bone and immune cells.
T cell protein tyrosine phosphatase (TCPTP), also known as protein-tyrosine phosphatase …