Background RNA interference (RNAi), a newly developed method in which RNA molecules
inhibit gene expression, has recently received considerable research attention. In the …

19 (4), 190–194. Agnesi, F., Bellini, R., & Ravotto, P.(2011). Profession of information and
communication technology (ICT) capability and professionalism in digital innovation: System …

Gene therapy might represent a promising strategy for chondral and osteochondral defects
repair by balancing the management of temporary joint mechanical incompetence with …

The overall burden associated with musculoskeletal (MSK) conditions surpasses that of
tobacco-related health effects, cancer, and diabetes (Barbour et al., 2017; United States …

Background: The treatment of cartilage damage is a hot topic at present, and cell therapy is
an emerging alternative therapy. Stem cells derived from peripheral blood have become the …

Background A combination of tissue engineering methods employing mesenchymal stem
cells (MSCs) together with gene transfer takes advantage of innovative strategies and …

The key principle of gene delivery to articulations by direct intra-articular injection is to
release complementary DNA (cDNA)-encoding medical products that will lead to …

A description of a proposed categorization scheme of regenerative stem cell therapies
illustrated by review of basic science and clinical studies involving the clinical application of …

Implantation of peripheral blood aspirates induced towards chondrogenic differentiation
upon genetic modification in sites of articular cartilage injury may represent a powerful …

Articular cartilage injuries have an inadequate aptitude to reproduce the original structure
and functions of this highly specialized tissue. As most of the currently available options also …