Free radicals are chemical species (atoms, molecules, or ions) containing one or more
unpaired electrons in their external orbitals and generally display a remarkable reactivity …

There is significant evidence that, in living systems, free radicals and other reactive oxygen
and nitrogen species play a double role, because they can cause oxidative damage and …

It is well established that the increase in reactive oxygen species (ROS) and free radicals
production during exercise has both positive and negative physiological effects. Among …

The first suggestion that physical exercise results in free radical-mediated damage to tissues
appeared in 1978, and the past three decades have resulted in a large growth of knowledge …

Scientific advances in this field have not only given us a better understanding of what is an
optimal diet, but has allowed food and nutraceutical companies to market products with …

Strenuous exercise increases oxygen consumption and causes disturbance of intracellular
pro‐oxidant–antioxidant homeostasis. The mitochondrial electron transport chain …

There is consistent evidence from human and animal studies that strenuous physical
exercise may induce a state wherein the antioxidant defenses of several tissues are …

Hypermetabolic state in hyperthyroidism is associated with tissue oxidative injury. Available
data indicate that hyperthyroid tissues exhibit an increased ROS and RNS production. The …

Epidemiologic investigations have shown that exercise reduces morbidity and mortality from
coronary artery disease. In this study, using a rat model, we attempted to determine whether …

Aging is associated with increased oxidative stress. Muscle levels of oxidative stress are
further elevated with exercise. The purpose of this study was to determine if dietary …