Background The biopharmaceuticals market has grown rapidly in recent years owing to the
low toxicity and high therapeutic efficacy of peptide and protein drugs. However, due to their …

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), also known as COVID-
19, is currently developing into a rapidly disseminating and an overwhelming worldwide …

Current study is focused to enhance the solubility of poorly soluble drug olanzapine (OLZ)
by nanogels drug delivery system, as improved solubility is one of the most important …

Ocular fungal infections can pose severe health conditions that may develop into vision
impairment and blindness. Sertaconazole (STZ) is a widely used antifungal; however, its low …

Current study aimed to develop a spray-dried powder containing indomethacin (IND)-loaded
polymeric micelles which can be administered perorally as a dissolved powder to enhance …

Purpose Nanotechnology-based drug delivery systems (nano-DDS) have been developed
to be a promising strategy to improve the efficacy, safety, physicochemical and …

Chitosan/alginate nanoparticles (DG1-NPs and DG1/Cur-NPs) aiming to enhance the oral
antithrombotic activity of clam heparinoid DG1 were prepared by ionotropic pre-gelation …

Encapsulating antigens with zeolitic imidazole framework-8 (ZIF-8) exhibits many
advantages in vaccine development. However, most viral antigens with complex particulate …

Aim The aim of this study was the development and in vivo evaluation of different types of
nanoemulsions for oral delivery of low molecular weight heparin (LMWH). Methods …

The present work investigates the targeting efficacy of a novel thiolated polymer-based
nanocomposite reinforced with glycyrrhetinic acid (GA) and loaded with 5-fluorouracil in …