Evaluation of different computational methods on 5-methylcytosine sites identification

H Lv, ZM Zhang, SH Li, JX Tan, W Chen… - Briefings in …, 2020 - academic.oup.com
Methylcytosine (m5C) plays an extremely important role in the basic biochemical process.
With the great increase of identified m5C sites in a wide variety of organisms, their …

Comparative analysis and prediction of quorum-sensing peptides using feature representation learning and machine learning algorithms

L Wei, J Hu, F Li, J Song, R Su… - Briefings in …, 2020 - academic.oup.com
Quorum-sensing peptides (QSPs) are the signal molecules that are closely associated with
diverse cellular processes, such as cell–cell communication, and gene expression …

mAHTPred: a sequence-based meta-predictor for improving the prediction of anti-hypertensive peptides using effective feature representation

B Manavalan, S Basith, TH Shin, L Wei, G Lee - Bioinformatics, 2019 - academic.oup.com
Motivation Cardiovascular disease is the primary cause of death globally accounting for
approximately 17.7 million deaths per year. One of the stakes linked with cardiovascular …

Exploring sequence-based features for the improved prediction of DNA N4-methylcytosine sites in multiple species

L Wei, S Luan, LAE Nagai, R Su, Q Zou - Bioinformatics, 2019 - academic.oup.com
Motivation As one of important epigenetic modifications, DNA N4-methylcytosine (4mC) is
recently shown to play crucial roles in restriction–modification systems. For better …

Design powerful predictor for mRNA subcellular location prediction in Homo sapiens

ZY Zhang, YH Yang, H Ding, D Wang… - Briefings in …, 2021 - academic.oup.com
Messenger RNAs (mRNAs) shoulder special responsibilities that transmit genetic code from
DNA to discrete locations in the cytoplasm. The locating process of mRNA might provide …

iProEP: a computational predictor for predicting promoter

HY Lai, ZY Zhang, ZD Su, W Su, H Ding… - … Therapy-Nucleic Acids, 2019 - cell.com
Promoter is a fundamental DNA element located around the transcription start site (TSS) and
could regulate gene transcription. Promoter recognition is of great significance in …

Perspectives of CRISPR/Cas-mediated cis-engineering in horticulture: unlocking the neglected potential for crop improvement

Q Li, M Sapkota, E van der Knaap - Horticulture research, 2020 - academic.oup.com
Directed breeding of horticultural crops is essential for increasing yield, nutritional content,
and consumer-valued characteristics such as shape and color of the produce. However …

[HTML][HTML] AtbPpred: a robust sequence-based prediction of anti-tubercular peptides using extremely randomized trees

B Manavalan, S Basith, TH Shin, L Wei… - Computational and …, 2019 - Elsevier
Mycobacterium tuberculosis is one of the most dangerous pathogens in humans. It acts as
an etiological agent of tuberculosis (TB), infecting almost one-third of the world's population …

iRNAD: a computational tool for identifying D modification sites in RNA sequence

ZC Xu, PM Feng, H Yang, WR Qiu, W Chen… - …, 2019 - academic.oup.com
Motivation Dihydrouridine (D) is a common RNA post-transcriptional modification found in
eukaryotes, bacteria and a few archaea. The modification can promote the conformational …

Prediction of regulatory motifs from human Chip-sequencing data using a deep learning framework

J Yang, A Ma, AD Hoppe, C Wang, Y Li… - Nucleic acids …, 2019 - academic.oup.com
The identification of transcription factor binding sites and cis-regulatory motifs is a frontier
whereupon the rules governing protein–DNA binding are being revealed. Here, we …