Principles of regulatory T cell function
S Dikiy, AY Rudensky - Immunity, 2023 - cell.com
Regulatory T (Treg) cells represent a distinct lineage of cells of the adaptive immune system
indispensable for forestalling fatal autoimmune and inflammatory pathologies. The role of …
indispensable for forestalling fatal autoimmune and inflammatory pathologies. The role of …
The impact of the gut microbiome on extra-intestinal autoimmune diseases
E Miyauchi, C Shimokawa, A Steimle… - Nature Reviews …, 2023 - nature.com
The prevalence of autoimmune diseases (ADs) worldwide has rapidly increased over the
past few decades. Thus, in addition to the classical risk factors for ADs, such as genetic …
past few decades. Thus, in addition to the classical risk factors for ADs, such as genetic …
Microbiome-based therapeutics
MT Sorbara, EG Pamer - Nature Reviews Microbiology, 2022 - nature.com
Symbiotic microorganisms inhabiting the gastrointestinal tract promote health by decreasing
susceptibility to infection and enhancing resistance to a range of diseases. In this Review …
susceptibility to infection and enhancing resistance to a range of diseases. In this Review …
Novel bile acid biosynthetic pathways are enriched in the microbiome of centenarians
Y Sato, K Atarashi, DR Plichta, Y Arai, S Sasajima… - Nature, 2021 - nature.com
Centenarians have a decreased susceptibility to ageing-associated illnesses, chronic
inflammation and infectious diseases 1, 2, 3. Here we show that centenarians have a distinct …
inflammation and infectious diseases 1, 2, 3. Here we show that centenarians have a distinct …
The gut-brain axis: how microbiota and host inflammasome influence brain physiology and pathology
A Rutsch, JB Kantsjö, F Ronchi - Frontiers in immunology, 2020 - frontiersin.org
The human microbiota has a fundamental role in host physiology and pathology. Gut
microbial alteration, also known as dysbiosis, is a condition associated not only with …
microbial alteration, also known as dysbiosis, is a condition associated not only with …
The role of short-chain fatty acids in the interplay between gut microbiota and diet in cardio-metabolic health
The gut microbiota plays an important role in cardio-metabolic diseases with diet being
among the strongest modulators of gut microbiota composition and function. Resistant …
among the strongest modulators of gut microbiota composition and function. Resistant …
Inflammatory bowel diseases (IBD) and the microbiome—searching the crime scene for clues
M Lee, EB Chang - Gastroenterology, 2021 - Elsevier
Inflammatory bowel diseases (IBD) develop via convergence of environmental, microbial,
immunological, and genetic factors. Alterations in the gut microbiota have been associated …
immunological, and genetic factors. Alterations in the gut microbiota have been associated …
Gut microbiome–brain alliance: a landscape view into mental and gastrointestinal health and disorders
Gut microbiota includes a vast collection of microorganisms residing within the
gastrointestinal tract. It is broadly recognized that the gut and brain are in constant …
gastrointestinal tract. It is broadly recognized that the gut and brain are in constant …
[HTML][HTML] Gut microbiota, inflammatory bowel disease and colorectal cancer
AEV Quaglio, TG Grillo, ECS De Oliveira… - World journal of …, 2022 - ncbi.nlm.nih.gov
The gut microbiota is a complex community of microorganisms that inhabit the digestive
tracts of humans, living in symbiosis with the host. Dysbiosis, characterized by an imbalance …
tracts of humans, living in symbiosis with the host. Dysbiosis, characterized by an imbalance …
[HTML][HTML] Regulation of intestinal barrier function by microbial metabolites
The human gastrointestinal tract (GI) harbors a diverse population of microbial life that
continually shapes host pathophysiological responses. Despite readily available abundant …
continually shapes host pathophysiological responses. Despite readily available abundant …