Epidemiology and burden of human papillomavirus and related diseases, molecular pathogenesis, and vaccine evaluation

AJ Kombe Kombe, B Li, A Zahid, HM Mengist… - Frontiers in public …, 2021 - frontiersin.org
Diagnosed in more than 90% of cervical cancers, the fourth deadliest cancer in women,
human papillomavirus (HPV) is currently the most common pathogen responsible for female …

Mucosal and cutaneous human papillomavirus infections and cancer biology

T Gheit - Frontiers in Oncology, 2019 - frontiersin.org
Papillomaviridae is a family of small non-enveloped icosahedral viruses with double-
stranded circular DNA. More than 200 different human papillomaviruses (HPVs) have been …

Genomic risk factors for cervical cancer

D Ramachandran, T Dörk - Cancers, 2021 - mdpi.com
Simple Summary Cervical cancer is the fourth leading cause of cancer-related deaths in
females worldwide. Despite an active immunisation strategy in many countries, high-risk …

Human papillomavirus 18 genetic variation and cervical cancer risk worldwide

AA Chen, T Gheit, S Franceschi, M Tommasino… - Journal of …, 2015 - Am Soc Microbiol
ABSTRACT Human papillomavirus 18 (HPV18) is the second most carcinogenic HPV type,
after HPV16, and it accounts for approximately 12% of squamous cell carcinoma (SCC) as …

[HTML][HTML] Global variation of human papillomavirus genotypes and selected genes involved in cervical malignancies

RSA Husain, V Ramakrishnan - Annals of global health, 2015 - Elsevier
Background Carcinoma of the cervix is ranked second among the top 5 cancers affecting
women globally. Parallel to other cancers, it is also a complex disease involving numerous …

Global evaluation of lineage-specific human papillomavirus capsid antigenicity using antibodies elicited by natural infection

G Kamuyu, F Coelho da Silva, V Tenet… - Nature …, 2024 - nature.com
Human Papillomavirus (HPV) type variants have been classified into lineages and
sublineages based upon their whole genome sequence. Here we have examined the …

Distribution of high risk human papillomavirus types in Western Kazakhstan-retrospective analysis of PCR data

YZ Bekmukhambetov… - Asian Pacific Journal …, 2016 - journal.waocp.org
Background: Virtually all cases of cervical cancer are caused by persistent infections with a
restricted set of human papillomaviruses (HPV). Cancer of the cervix is the third or even the …

Emerging biomarkers and clinical significance of HPV genotyping in prevention and management of cervical cancer

UJ Shah, M Nasiruddin, SA Dar, MKA Khan… - Microbial …, 2020 - Elsevier
Cervical cancer is a growing and serious problem world-wide in women, but more acute in
developing countries especially in Indian subcontinent. The main causative agent for the …

[HTML][HTML] In silico analysis of HLA-1 and HLA-2 recognition of a designed recombinant human papillomavirus vaccine based on L1 protein HPV subtype 45

A Sulfianti, N Karimah, A Nurhasanah - Journal of Genetic Engineering and …, 2023 - Elsevier
Background Human leukocyte antigen (HLA) can bind and present the processed antigenic
peptide derived from the vaccine to the T cell receptor, and this capability is crucial in …

Genetic diversity of HPV16 and HPV18 in Brazilian patients with invasive cervical cancer

JPCB Vidal, SP Felix, CBP Chaves… - Journal of medical …, 2016 - Wiley Online Library
Cervical cancer is the fourth most common cancer among women, and∼ 70–80% of these
cancers are associated with two human papillomavirus types: HPV16 and HPV18. Several …