Sulfonyl fluorides as targets and substrates in the development of new synthetic methods
The advent of sulfur (vi)-fluoride exchange (SuFEx) processes as transformations with click-
like reactivity has invigorated research into electrophilic species featuring a sulfur–fluorine …
like reactivity has invigorated research into electrophilic species featuring a sulfur–fluorine …
[HTML][HTML] Triazoles and their derivatives: Chemistry, synthesis, and therapeutic applications
Among the nitrogen-containing heterocyclic compounds, triazoles emerge with superior
pharmacological applications. Structurally, there are two types of five-membered triazoles: 1 …
pharmacological applications. Structurally, there are two types of five-membered triazoles: 1 …
EnT-mediated N–S bond homolysis of a bifunctional reagent leading to aliphatic sulfonyl fluorides
JE Erchinger, R Hoogesteger, R Laskar… - Journal of the …, 2023 - ACS Publications
Sulfur (VI) fluoride exchange (SuFEx) gives rise to a plethora of high-valent sulfur linkages;
however, the availability of (aliphatic) sulfonyl fluoride manifolds lag behind, owing to the …
however, the availability of (aliphatic) sulfonyl fluoride manifolds lag behind, owing to the …
The growing applications of SuFEx click chemistry
SuFEx (Sulfur Fluoride Exchange) is a modular, next generation family of click reactions,
geared towards the rapid and reliable assembly of functional molecules. This review …
geared towards the rapid and reliable assembly of functional molecules. This review …
SuFExable polymers with helical structures derived from thionyl tetrafluoride
Sulfur (vi) fluoride exchange (SuFEx) is a category of click chemistry that enables covalent
linking of modular units through sulfur (vi) connective hubs. The efficiency of SuFEx and the …
linking of modular units through sulfur (vi) connective hubs. The efficiency of SuFEx and the …
Electrochemical Oxo‐Fluorosulfonylation of Alkynes under Air: Facile Access to β‐Keto Sulfonyl Fluorides
D Chen, X Nie, Q Feng, Y Zhang… - Angewandte Chemie …, 2021 - Wiley Online Library
Radical fluorosulfonylation is emerging as an appealing approach for the synthesis of
sulfonyl fluorides, which have widespread applications in many fields, in particular in the …
sulfonyl fluorides, which have widespread applications in many fields, in particular in the …
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
Sulfur fluoride exchange (SuFEx) has emerged as the new generation of click chemistry. We
report here a SuFEx-enabled, agnostic approach for the discovery and optimization of …
report here a SuFEx-enabled, agnostic approach for the discovery and optimization of …
Emerging building blocks for medicinal chemistry: recent synthetic advances
OO Grygorenko, DM Volochnyuk… - European Journal of …, 2021 - Wiley Online Library
Current medicinal chemistry relies heavily on the quality of building blocks, ie reagents used
to introduce chemical diversity into the target molecules. The last decade witnessed an …
to introduce chemical diversity into the target molecules. The last decade witnessed an …
Introducing A New Class of Sulfonyl Fluoride Hubs via Radical Chloro‐Fluorosulfonylation of Alkynes
X Nie, T Xu, Y Hong, H Zhang, C Mao… - Angewandte Chemie …, 2021 - Wiley Online Library
Sulfonyl fluorides have widespread applications in many important fields, including ligation
chemistry, chemical biology, and drug discovery. Therefore, new methods to increase the …
chemistry, chemical biology, and drug discovery. Therefore, new methods to increase the …
Linkage chemistry of S (VI) fluorides
D Zeng, WP Deng, X Jiang - Chemistry–A European Journal, 2023 - Wiley Online Library
Sulfur (VI)‐fluoride exchange linkage as a next generation of click chemistry was introduced
by Sharpless and coworkers in 2014. Distinguished from CuAAC, the SuFEx reaction …
by Sharpless and coworkers in 2014. Distinguished from CuAAC, the SuFEx reaction …