Theoretical and computational hierarchical nanomechanics of protein materials: Deformation and fracture

MJ Buehler, S Keten, T Ackbarow - Progress in Materials Science, 2008 - Elsevier
Proteins constitute the building blocks of biological materials such as tendon, bone, skin,
spider silk or cells. An important trait of these materials is that they display highly …

Atomic force microscopy (AFM) and its applications to bone-related research

Y Zhou, J Du - Progress in Biophysics and Molecular Biology, 2022 - Elsevier
Bone consists of organic (mostly collagen) and inorganic (mostly bioapatite mineral)
components that are organized into hierarchical structures from nano-to macro-scales that …

Nature designs tough collagen: explaining the nanostructure of collagen fibrils

MJ Buehler - Proceedings of the National Academy of …, 2006 - National Acad Sciences
Collagen is a protein material with superior mechanical properties. It consists of collagen
fibrils composed of a staggered array of ultra-long tropocollagen (TC) molecules. Theoretical …

Thermal denaturation studies of collagen by microthermal analysis and atomic force microscopy

L Bozec, M Odlyha - Biophysical journal, 2011 - cell.com
The structural properties of collagen have been the subject of numerous studies over past
decades, but with the arrival of new technologies, such as the atomic force microscope and …

Nanomechanics of collagen fibrils under varying cross-link densities: atomistic and continuum studies

MJ Buehler - Journal of the mechanical behavior of biomedical …, 2008 - Elsevier
Collagen is a protein material with intriguing mechanical properties—it is highly elastic,
shows large fracture strength and plays a crucial role in making Nature's structural materials …

Dissolution and regeneration of collagen fibers using ionic liquid

Z Meng, X Zheng, K Tang, J Liu, Z Ma… - International Journal of …, 2012 - Elsevier
Native skin collagen fibers were successfully dissolved in the ionic liquid, 1-butyl-3-
methylimidazolium chloride ([BMIM] Cl), and regenerated in different precipitators. The …

Atomic force microscopy and indentation force measurement of bone

PJ Thurner - Wiley Interdisciplinary Reviews: Nanomedicine …, 2009 - Wiley Online Library
This review is summarizing the results obtained from atomic force microscopy (AFM) and
nanoindentation experiments to date. The combination of both techniques is especially …

Applications of atomic force microscopy for the assessment of nanoscale morphological and mechanical properties of bone

JM Wallace - Bone, 2012 - Elsevier
Scanning probe microscopy (SPM) has been in use for 30years, and the form of SPM known
as atomic force microscopy (AFM) has been around for 25 of those years. AFM has been …

3D scanning SAXS: A novel method for the assessment of bone ultrastructure orientation

M Georgiadis, M Guizar-Sicairos, A Zwahlen… - Bone, 2015 - Elsevier
The arrangement and orientation of the ultrastructure plays an important role for the
mechanical properties of inhomogeneous and anisotropic materials, such as polymers …

Biomechanical and biophysical environment of bone from the macroscopic to the pericellular and molecular level

L Ren, P Yang, Z Wang, J Zhang, C Ding… - Journal of the mechanical …, 2015 - Elsevier
Bones with complicated hierarchical configuration and microstructures constitute the load-
bearing system. Mechanical loading plays an essential role in maintaining bone health and …