Fibrotic diseases cause annually more than 800,000 deaths worldwide, whereof the majority
accounts for lung and cardiac fibrosis. A pathological remodeling of the extracellular matrix …

Coronary arterial disease is the most common cardiovascular disease. Myocardial ischemia-
reperfusion injury caused by the initial interruption of organ blood flow and subsequent …

This study evaluated the safety and feasibility of transendocardial injections of VentriGel, a
cardiac extracellular matrix hydrogel, in early and late post–myocardial infarction (MI) …

Alginate hydrogels are extremely versatile and adaptable biomaterials, with great potential
for use in biomedical applications. Their extracellular matrix-like features have been key …

An auxetic conductive cardiac patch (AuxCP) for the treatment of myocardial infarction (MI) is
introduced. The auxetic design gives the patch a negative Poisson's ratio, providing it with …

The excessive reactive oxygen species (ROS) and hypoxia deteriorate the inflammation‐
related diseases such as myocardial infarction (MI), and thereby deter the normal tissue …

Alginate biomaterial is widely utilized for tissue engineering and regeneration due to its
biocompatibility, non-thrombogenic nature, mild and physical gelation process, and the …

Poly (glycerol sebacate)(PGS) is a biodegradable polymer increasingly used in a variety of
biomedical applications. This polyester is prepared by polycondensation of glycerol and …

New therapies are needed to prevent heart failure after myocardial infarction (MI). As
experimental treatment strategies for MI approach translation, safety and efficacy must be …

Cardiovascular disease is a leading cause of mortality in the world and is exacerbated by
the presence of cardiac fibrosis, defined by the accumulation of noncontractile extracellular …