COVID-19 and liver disease: mechanistic and clinical perspectives

T Marjot, GJ Webb, AS Barritt IV, AM Moon… - Nature reviews …, 2021 - nature.com
Our understanding of the hepatic consequences of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection and its resultant coronavirus disease 2019 (COVID …

Body localization of ACE-2: on the trail of the keyhole of SARS-CoV-2

F Salamanna, M Maglio, MP Landini, M Fini - Frontiers in medicine, 2020 - frontiersin.org
The explosion of the new coronavirus (SARS-CoV-2) pandemic has brought the role of the
angiotensin converting enzyme 2 (ACE2) back into the scientific limelight. Since SARS-CoV …

Clinical characteristics of non‐ICU hospitalized patients with coronavirus disease 2019 and liver injury: a retrospective study

H Xie, J Zhao, N Lian, S Lin, Q Xie, H Zhuo - Liver international, 2020 - Wiley Online Library
Abstract Background & Aims Coronavirus disease 2019 (COVID‐19) has raised world
concern for global epidemic since December, 2019. Limited data are available for liver …

Coronavirus disease (COVID-19) and the liver: a comprehensive systematic review and meta-analysis

P Kumar-M, S Mishra, DK Jha, J Shukla… - Hepatology …, 2020 - Springer
Background Liver function derangements have been reported in coronavirus disease
(COVID-19), but reported rates are variable. Methods We searched PubMed and Embase …

[HTML][HTML] Liver disease and outcomes among COVID-19 hospitalized patients–a systematic review and meta-analysis

A Sharma, P Jaiswal, Y Kerakhan, L Saravanan… - Annals of hepatology, 2021 - Elsevier
Introduction and objectives The coronavirus disease 2019 (COVID-19) pandemic has been
a challenge globally. In severe acute respiratory syndrome (SARS) epidemic 60% of …

Recent advances in the angiotensin‐converting enzyme 2–angiotensin (1–7)–Mas axis

RAS Santos, AJ Ferreira… - Experimental …, 2008 - Wiley Online Library
In the past few years, the classical concept of the renin–angiotensin system (RAS) has
experienced substantial conceptual changes. The identification of: the renin/prorenin …

Sex differences in renal angiotensin converting enzyme 2 (ACE2) activity are 17β-oestradiol-dependent and sex chromosome-independent

J Liu, H Ji, W Zheng, X Wu, JJ Zhu, AP Arnold… - Biology of sex …, 2010 - Springer
Background Angotensin converting enzyme 2 (ACE2) is a newly discovered
monocarboxypeptidase that counteracts the vasoconstrictor effects of angiotensin II (Ang II) …

Interplay of cardiovascular mediators, oxidative stress and inflammation in liver disease and its complications

C Matyas, G Haskó, L Liaudet, E Trojnar… - Nature Reviews …, 2021 - nature.com
The liver is a crucial metabolic organ that has a key role in maintaining immune and
endocrine homeostasis. Accumulating evidence suggests that chronic liver disease might …

Angiotensin-(1–7): beyond the cardio-renal actions

DG Passos-Silva, T Verano-Braga… - Clinical …, 2013 - portlandpress.com
It is well known that the RAS (renin–angiotensin system) plays a key role in the modulation
of many functions in the body. AngII (angiotensin II) acting on AT1R (type 1 AngII receptor) …

Potential effects of coronaviruses on the liver: an update

X Wang, J Lei, Z Li, L Yan - Frontiers in Medicine, 2021 - frontiersin.org
The coronaviruses that cause notable diseases, namely, severe acute respiratory syndrome
(SARS), middle east respiratory syndrome (MERS) and coronavirus disease 2019 (COVID …