The persistence of the human malaria parasite Plasmodium falciparum during blood stage
proliferation in its host depends on the successive expression of variant molecules at the …

Telomerase is a eukaryotic ribonucleoprotein (RNP) whose specialized reverse
transcriptase action performs de novo synthesis of one strand of telomeric DNA. The …

Recent studies into the global causes of severe diarrhoea in young children have identified
the protozoan parasite Cryptosporidium as the second most important diarrhoeal pathogen …

Background It has been shown that nearly a quarter of the initial predicted gene models in
the Plasmodium falciparum genome contain errors. Although there have been efforts to …

Recent advances in high‐throughput sequencing present a new opportunity to deeply probe
an organism's transcriptome. In this study, we used Illumina‐based massively parallel …

To elucidate the molecular nature of evolutionary changes of telomeres in the plant order
Asparagales, we aimed to characterize telomerase RNA subunits (TRs) in these plants. The …

Background In eukaryotic organisms, gene expression is regulated at multiple levels during
the processes of transcription and translation. The absence of a tight regulatory network for …

In eukaryotic organisms, noncoding RNAs (ncRNAs) have been implicated as important
regulators of multifaceted biological processes, including transcriptional, posttranscriptional …

Malaria is a significant threat throughout the developing world. Among the most fascinating
aspects of the protozoan parasites responsible for this disease are the methods they employ …

Here we describe the ways in which the sequence and annotation of the Plasmodium
falciparum reference genome has changed since its publication in 2002. As the malaria …