The medicinal chemistry of Urtica dioica L.: from preliminary evidence to clinical studies supporting its neuroprotective activity

P Semwal, A Rauf, A Olatunde, P Singh… - Natural products and …, 2023 - Springer
Urtica dioica is a perennial herb from the family of Urticaceae that is commonly known as
stinging nettle. This plant is widespread in Europe, Africa, America, and a part of Asia, as it …

Plants used for the treatment of diabetes in Jordan: A review of scientific evidence

A Al-Aboudi, FU Afifi - Pharmaceutical biology, 2011 - Taylor & Francis
Context: Diabetes is a serious disease which has reached epidemic proportions in many
parts of the world. Despite the tremendous developments in medicinal chemistry, traditional …

Beneficial effects of Urtica dioica on scopolamine-induced memory impairment in rats: protection against acetylcholinesterase activity and neuronal oxidative damage

S Ghasemi, M Moradzadeh, M Hosseini… - Drug and chemical …, 2019 - Taylor & Francis
This study was conducted to investigate protective effects of Urtica dioica extract on
acetylcholinesterase (AChE) activity and the oxidative damage of brain tissues in …

Iranian medicinal plants for diabetes mellitus: a systematic review.

AA Rashidi, SM Mirhashemi, M Taghizadeh… - Pakistan journal of …, 2013 - europepmc.org
In the Iranian traditional medicine a significant usage of herbs is promoted for their anti-
diabetic activity. The aim of this review to assess the efficacy of glucose lowering effects of …

Medicinal plants for diabetes associated neurodegenerative diseases: A systematic review of preclinical studies

H Khazaei, M Pesce, A Patruno, IY Aneva… - Phytotherapy …, 2021 - Wiley Online Library
Diabetes mellitus is a metabolic defect with many complications for the patients. Deaths due
to diabetes and its complications are increasing, and one of the most serious consequences …

Review of the effect of natural compounds and extracts on neurodegeneration in animal models of diabetes mellitus

C Infante-Garcia, M Garcia-Alloza - International journal of molecular …, 2019 - mdpi.com
Diabetes mellitus is a chronic metabolic disease with a high prevalence in the Western
population. It is characterized by pancreas failure to produce insulin, which involves high …

Effect of Urtica dioica on memory dysfunction and hypoalgesia in an experimental model of diabetic neuropathy

SS Patel, M Udayabanu - Neuroscience Letters, 2013 - Elsevier
Diabetic neuropathy is considered as a disease of the peripheral nervous system, but recent
evidences suggest the involvement of central nervous system as well. In this study we …

Urtica dioica modulates hippocampal insulin signaling and recognition memory deficit in streptozotocin induced diabetic mice

SS Patel, S Gupta, M Udayabanu - Metabolic brain disease, 2016 - Springer
Diabetes mellitus has been associated with functional abnormalities in the hippocampus
and performance of cognitive function. Urtica dioica (UD) has been used in the treatment of …

Diabetes mellitus and its management with medicinal plants: A perspective based on Iranian research

A Rezaei, A Farzadfard, A Amirahmadi, M Alemi… - Journal of …, 2015 - Elsevier
Ethnopharmacological relevance Complementary and alternative medicine has been
increasingly used to treat chronic illnesses, such as diabetes mellitus. However, various …

Urtica dioica leaves modulates muscarinic cholinergic system in the hippocampus of streptozotocin-induced diabetic mice

SS Patel, A Parashar, M Udayabanu - Metabolic brain disease, 2015 - Springer
Diabetes mellitus is a chronic metabolic disorder and has been associated with cognitive
dysfunction. In our earlier study, chronic Urtica dioica (UD) treatment significantly …