The treat-to-target (T2T) concept has improved outcomes for patients with diabetes,
hypertension and rheumatoid arthritis. This therapeutic strategy involves choosing a well …

Objective To achieve consensus on a definition of remission in SLE (DORIS). Background
Remission is the stated goal for both patient and caregiver, but consensus on a definition of …

Background Remission and low disease activity (LDA) have been proposed as the treatment
goals for patients with systemic lupus erythematosus (SLE). Several definitions for each …

Objectives To investigate the impact of remission and lupus low disease activity state
(LLDAS) on health-related quality of life (HRQoL) in systemic lupus erythematosus. Methods …

Aim We investigated plasma sirtuin‐1 (SIRT1) levels in systemic lupus erythematosus (SLE)
patients, and discussed potential of plasma SIRT1 as a biomarker for SLE. Methods A total …

Background Remission or the lowest possible disease activity is the main target in the
management of systemic lupus erythematosus (SLE). Anyway, conflicting data are present in …

A few decades ago, the therapy goal of patients with systemic lupus erythematosus (SLE)
was survival and the prevention of organ failure. Today, clinical remission and low disease …

Treat-to-target is a therapeutic approach based on adjustments to treatment at set intervals
in order to achieve well-defined, clinically relevant targets. This approach has been …

Background Flares in patients with SLE, regardless of their severity, have been associated
with damage accrual. However, their impact on health-related quality of life (HRQoL) has not …

Objective To systematically review and evaluate the prevalence, potential predictors, and
prognostic benefits of remission achievement in patients with systemic lupus erythematosus …