The SARS‐CoV‐2 main protease (Mpro): Structure, function, and emerging therapies for COVID‐19
Q Hu, Y Xiong, GH Zhu, YN Zhang, YW Zhang… - MedComm, 2022 - Wiley Online Library
The main proteases (Mpro), also termed 3‐chymotrypsin‐like proteases (3CLpro), are a
class of highly conserved cysteine hydrolases in β‐coronaviruses. Increasing evidence has …
class of highly conserved cysteine hydrolases in β‐coronaviruses. Increasing evidence has …
Protease targeted COVID-19 drug discovery and its challenges: Insight into viral main protease (Mpro) and papain-like protease (PLpro) inhibitors
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) brutally perils physical and
mental health worldwide. Unavailability of effective anti-viral drug rendering global threat of …
mental health worldwide. Unavailability of effective anti-viral drug rendering global threat of …
Evaluation of green tea polyphenols as novel corona virus (SARS CoV-2) main protease (Mpro) inhibitors – an in silico docking and molecular dynamics simulation …
R Ghosh, A Chakraborty, A Biswas… - Journal of Biomolecular …, 2021 - Taylor & Francis
Abstract Coronavirus disease 2019 (COVID-19) is a viral respiratory disease which caused
global health emergency and announced as pandemic disease by World Health …
global health emergency and announced as pandemic disease by World Health …
Plants metabolites: possibility of natural therapeutics against the COVID-19 pandemic
COVID-19, a disease induced by SARS-CoV-2 (Severe Acute Respiratory Syndrome
Coronavirus-2), has been the cause of a worldwide pandemic. Though extensive research …
Coronavirus-2), has been the cause of a worldwide pandemic. Though extensive research …
A review on drug repurposing applicable to COVID-19
S Dotolo, A Marabotti, A Facchiano… - Briefings in …, 2021 - academic.oup.com
Drug repurposing involves the identification of new applications for existing drugs at a lower
cost and in a shorter time. There are different computational drug-repurposing strategies and …
cost and in a shorter time. There are different computational drug-repurposing strategies and …
Current prevention of COVID-19: natural products and herbal medicine
Starting from December 2019, novel coronavirus disease 2019 (COVID-19) pandemic has
caused tremendous economic loss and unprecedented health crisis across the globe. While …
caused tremendous economic loss and unprecedented health crisis across the globe. While …
Identification of bioactive molecule from Withania somnifera (Ashwagandha) as SARS-CoV-2 main protease inhibitor
SARS-CoV-2 is the causative agent of COVID-19 and has been declared as pandemic
disease by World Health Organization. Lack of targeted therapeutics and vaccines for …
disease by World Health Organization. Lack of targeted therapeutics and vaccines for …
A global picture: therapeutic perspectives for COVID-19
VP Chavda, C Kapadia, S Soni, R Prajapati… - …, 2022 - Taylor & Francis
The COVID-19 pandemic is a lethal virus outbreak by severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2), which has severely affected human lives and the global …
coronavirus-2 (SARS-CoV-2), which has severely affected human lives and the global …
Flavonols as potential antiviral drugs targeting SARS-CoV-2 proteases (3CLpro and PLpro), spike protein, RNA-dependent RNA polymerase (RdRp) and angiotensin …
The novel coronavirus outbreak (COVID-19) caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) represents the actual greatest global public health crisis. The …
coronavirus 2 (SARS-CoV-2) represents the actual greatest global public health crisis. The …
Withanone and caffeic acid phenethyl ester are predicted to interact with main protease (Mpro) of SARS-CoV-2 and inhibit its activity
The recent novel coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-
CoV-2/2019-nCoV) has caused a large number of deaths around the globe. There is an …
CoV-2/2019-nCoV) has caused a large number of deaths around the globe. There is an …