Coronaviruses have exceptionally large RNA genomes of approximately 30 kilobases.
Genome replication and transcription is mediated by a multisubunit protein complex …

In the realm of nucleic acid structures, secondary structure forms a conceptually important
intermediate level of description and explains the dominating part of the free energy of …

The IntaRNA algorithm enables fast and accurate prediction of RNA–RNA hybrids by
incorporating seed constraints and interaction site accessibility. Here, we introduce …

Autosomal-recessive loss of the NSUN2 gene has been identified as a causative link to
intellectual disability disorders in humans. NSun2 is an RNA methyltransferase modifying …

CopraRNA (Comparative prediction algorithm for small RNA targets) is the most recent asset
to the Freiburg RNA Tools webserver. It incorporates and extends the functionality of the …

Clostridium difficile is an emergent pathogen, and the most common cause of nosocomial
diarrhea. In an effort to understand the role of small noncoding RNAs (sRNAs) in C. difficile …

Small RNAs (sRNAs) constitute a large and heterogeneous class of bacterial gene
expression regulators. Much like eukaryotic microRNAs, these sRNAs typically target …

RNA is a large group of functionally important biomacromolecules. In striking analogy to
proteins, the function of RNA depends on its structure and dynamics, which in turn is …

Transforming growth factor β (TGF-β)/Smad3 signaling plays a role in tissue fibrosis. We
report here that Erbb4-IR is a novel long non-coding RNA (lncRNA) responsible for TGF …

The ViennaRNA package is a widely used collection of programs for thermodynamic RNA
secondary structure prediction. Over the years, many additional tools have been developed …