Peripheral T cell populations are maintained by production of naive T cells in the thymus,
clonal expansion of activated cells, cellular self-renewal (or homeostatic proliferation), and …

A small subset of human immunodeficiency virus type 1 (HIV-1)-infected, therapy-naive
individuals–referred to as long-term non-progressors (LTNPs)–maintain a favourable course …

The majority of HIV-1 elite controllers (EC) restrict HIV-1 replication through highly functional
HIV-1-specific T cell responses, but mechanisms supporting the evolution of effective HIV-1 …

Mucosal-associated invariant T (MAIT) cells are characterized by the combined expression
of the semi-invariant T cell receptor (TCR) Vα7. 2, the lectin receptor CD161, as well as IL …

Elite controllers maintain undetectable levels of HIV-1 replication in the absence of
antiretroviral therapy, but the correlates of immune protection in this patient population are ill …

In the present review, we shall discuss the different components of the HIV-specific immune
response elicited by the infection, the kinetics of these responses during primary infection …

In the early days of the HIV epidemic, it was observed that a minority of the infected patients
did not progress to AIDS or death and maintained stable CD4+ cell counts. As the technique …

HIV infection is multi-faceted and a multi-step process. The virus-induced pathogenic
mechanisms are manifold and mediated through a range of positive and negative feedback …

Elite controllers (ECs) are rare individuals able to naturally control HIV-1 replication below
the detection limit of viral load (VL) commercial assays. It is unclear, however, whether ECs …

Background: The mechanisms behind natural control of HIV replication are still unclear, and
several studies pointed that elite controllers (ECs) are a heterogeneous group. Methods: We …