NMDA receptor functions in health and disease: Old actor, new dimensions
N-Methyl-D-aspartate ionotropic glutamate receptors (NMDARs) play key roles in
synaptogenesis, synaptic maturation, long-term plasticity, neuronal network activity, and …
synaptogenesis, synaptic maturation, long-term plasticity, neuronal network activity, and …
MMP‐9 in translation: from molecule to brain physiology, pathology, and therapy
B Vafadari, A Salamian… - Journal of …, 2016 - Wiley Online Library
Abstract Matrix metalloproteinase‐9 (MMP‐9) is a member of the metzincin family of mostly
extracellularly operating proteases. Despite the fact that all of these enzymes might be target …
extracellularly operating proteases. Despite the fact that all of these enzymes might be target …
Synaptopathies: synaptic dysfunction in neurological disorders–A review from students to students
K Lepeta, MV Lourenco, BC Schweitzer… - Journal of …, 2016 - Wiley Online Library
Synapses are essential components of neurons and allow information to travel coordinately
throughout the nervous system to adjust behavior to environmental stimuli and to control …
throughout the nervous system to adjust behavior to environmental stimuli and to control …
Crosstalk between glia, extracellular matrix and neurons
I Song, A Dityatev - Brain research bulletin, 2018 - Elsevier
Extracellular matrix (ECM) molecules in the central nervous system form highly organized
ECM structures around cell somata, axon initial segments, and synapses and play …
ECM structures around cell somata, axon initial segments, and synapses and play …
MMPs in learning and memory and neuropsychiatric disorders
Matrix metalloproteinases (MMPs) are a group of over twenty proteases, operating chiefly
extracellularly to cleave components of the extracellular matrix, cell adhesion molecules as …
extracellularly to cleave components of the extracellular matrix, cell adhesion molecules as …
Structural plasticity upon learning: regulation and functions
P Caroni, F Donato, D Muller - Nature Reviews Neuroscience, 2012 - nature.com
Recent studies have provided long-sought evidence that behavioural learning involves
specific synapse gain and elimination processes, which lead to memory traces that influence …
specific synapse gain and elimination processes, which lead to memory traces that influence …
The dual role of the extracellular matrix in synaptic plasticity and homeostasis
A Dityatev, M Schachner, P Sonderegger - Nature Reviews …, 2010 - nature.com
Recent studies have deepened our understanding of multiple mechanisms by which
extracellular matrix (ECM) molecules regulate various aspects of synaptic plasticity and …
extracellular matrix (ECM) molecules regulate various aspects of synaptic plasticity and …
A delicate balance: role of MMP-9 in brain development and pathophysiology of neurodevelopmental disorders
The extracellular matrix (ECM) is a critical regulator of neural network development and
plasticity. As neuronal circuits develop, the ECM stabilizes synaptic contacts, while its …
plasticity. As neuronal circuits develop, the ECM stabilizes synaptic contacts, while its …
Astroglial cradle in the life of the synapse
A Verkhratsky, M Nedergaard - … Transactions of the …, 2014 - royalsocietypublishing.org
Astroglial perisynaptic sheath covers the majority of synapses in the central nervous system.
This glial coverage evolved as a part of the synaptic structure in which elements directly …
This glial coverage evolved as a part of the synaptic structure in which elements directly …
Regulation of NMDA glutamate receptor functions by the GluN2 subunits
The N‐methyl‐D‐aspartate receptors (NMDARs) are ionotropic glutamate receptors that
mediate the flux of calcium (Ca2+) into the post‐synaptic compartment. Ca2+ influx …
mediate the flux of calcium (Ca2+) into the post‐synaptic compartment. Ca2+ influx …