[HTML][HTML] Selecting controls is not selecting “normals”: design and analysis issues for studying the etiology of polycystic ovary syndrome

MS Bloom, EF Schisterman, ML Hediger - Fertility and sterility, 2006 - Elsevier
INTRODUCTION: Polycystic ovary syndrome (PCOS) is a highly prevalent disorder among
postmenarcheal premenopausal women, accounting for much of anovulatory infertility, and it …

Pharmacological and therapeutic properties of valproate: a summary after 35 years of clinical experience

E Perucca - CNS drugs, 2002 - Springer
Thirty-five years since its introduction into clinical use, valproate (valproic acid) has become
the most widely prescribed antiepileptic drug (AED) worldwide. Its pharmacological effects …

Endocrine and metabolic adverse effects of psychotropic medications in children and adolescents

CU Correll, HE Carlson - Journal of the American Academy of Child & …, 2006 - Elsevier
OBJECTIVE:: Despite increasing use of psychotropic medications in children and
adolescents, data regarding their efficacy and safety are limited. Endocrine and metabolic …

[HTML][HTML] Interactions between antiepileptic drugs and hormones

S Svalheim, L Sveberg, M Mochol, E Taubøll - Seizure, 2015 - Elsevier
Antiepileptic drugs (AEDs) are known to have endocrine side effects in both men and
women. These can affect fertility, sexuality, thyroid function, and bone health, all functions of …

Olanzapine‐associated diabetes mellitus

EA Koller, PM Doraiswamy - Pharmacotherapy: The Journal of …, 2002 - Wiley Online Library
Study Objective. To explore the clinical characteristics of hyperglycemia in patients treated
with olanzapine. Design. Retrospective, epidemiologic survey of spontaneously reported …

Effect of antiepileptic drugs on reproductive endocrine function in individuals with epilepsy

JIT Isojärvi, E Taubøll, AG Herzog - CNS drugs, 2005 - Springer
It is well known that epilepsy, antiepileptic drugs (AEDs), and the reproductive system have
complex interactions. Fertility is lower in both men and women with epilepsy than in the …

Epilepsy, antiepileptic drugs, and the risk of major cardiovascular events

E Lee‐Lane, F Torabi, A Lacey… - …, 2021 - Wiley Online Library
Objective This study was undertaken to determine whether epilepsy and antiepileptic drugs
(including enzyme‐inducing and non‐enzyme‐inducing drugs) are associated with major …

Valproate potentiates androgen biosynthesis in human ovarian theca cells

VL Nelson-DeGrave, JK Wickenheisser… - …, 2004 - academic.oup.com
In patients with epilepsy, treatment with valproate (VPA) has been reported to be associated
with polycystic ovary syndrome-like symptoms including weight gain, hyperandrogenemia …

The reproductive safety profile of mood stabilizers, atypical antipsychotics, and broad-spectrum psychotropics

CL Ernst, JF Goldberg - Journal of Clinical Psychiatry, 2002 - psychiatrist.com
There has been growing concern about the potential iatrogenic effects of several newer
psychotropic drugs on reproductive health safety in women. Areas of particular concern in …

Abnormal gene expression profiles in human ovaries from polycystic ovary syndrome patients

E Jansen, JSE Laven, HBR Dommerholt… - Molecular …, 2004 - academic.oup.com
Polycystic ovary syndrome (PCOS) represents the most common cause of anovulatory
infertility and affects 5–10% of women of reproductive age. The etiology of PCOS is still …