Amino acid metabolism regulates essential cellular functions, not only by fueling protein
synthesis, but also by supporting the biogenesis of nucleotides, redox factors and lipids …

Copper is an essential trace element in the human body that is extensively distributed
throughout various tissues. The appropriate level of copper is crucial to maintaining the life …

Bone as a vigorous tissue is constantly undergoing bone remodeling. The homeostasis of
bone remodeling requires combined efforts of multifarious bone cells. Amino acids (AA) …

Chondrosarcomas are the most common malignancy of cartilage and are associated with
somatic mutations in isocitrate dehydrogenase 1 (IDH1) and IDH2 genes. Somatic IDH …

Enchondromas are a common tumor in bone that can occur as multiple lesions in
enchondromatosis, which is associated with deformity of the affected bone. These lesions …

Osteoclasts are bone resorbing cells that are essential to maintain skeletal integrity and
function. While many of the growth factors and molecular signals that govern …

旨在探讨谷氨酰胺在牛分枝杆菌卡介苗(Bacille Calmette-Guerin vaccine, BCG)
感染巨噬细胞过程中对凋亡的调控作用. 本文采用小鼠单核巨噬细胞RAW264. 7 …

Cancer cells have adapted to rapid tumor growth and evade immune attack by
reprogramming their metabolic pathways. Glutamine is an important nitrogen resource for …

Simple Summary Grade 2 and 3 and dedifferentiated chondrosarcomas represent rare
malignant bone neoplasms. These tumors are often associated with isocitrate …

Enchondromas are a common tumor in bone that can occur as multiple lesions in
enchondromatosis, which is associated with deformity of the effected bone. These lesions …