[HTML][HTML] Current status of human papillomavirus-related head and neck cancer: from viral genome to patient care

H Dong, X Shu, Q Xu, C Zhu, AM Kaufmann, ZM Zheng… - Virologica Sinica, 2021 - Springer
Human papillomavirus (HPV) infection identified as a definitive human carcinogen is
increasingly being recognized for its role in carcinogenesis of human cancers. Up to 38 …

[HTML][HTML] The immune microenvironment of HPV-positive and HPV-negative oropharyngeal squamous cell carcinoma: A multiparametric quantitative and spatial …

A Tosi, B Parisatto, A Menegaldo, G Spinato… - Journal of Experimental …, 2022 - Springer
Background Immune checkpoint inhibitors (ICI) are approved for treatment of recurrent or
metastatic oropharyngeal head and neck squamous cell carcinoma in the first-and second …

Noncanonical HPV carcinogenesis drives radiosensitization of head and neck tumors

TP Schrank, A Kothari, WH Weir… - Proceedings of the …, 2023 - National Acad Sciences
We analyzed transcriptional data from 104 HPV+ (Human papillomavirus) HNSCC (head
and neck squamous cell carcinoma) tumors together with two publicly available sources to …

[HTML][HTML] Potential Transcript-Based Biomarkers Predicting Clinical Outcomes of HPV-Positive Head and Neck Squamous Cell Carcinoma Patients

JO Muñoz-Bello, SL Romero-Córdoba… - Cells, 2024 - mdpi.com
Human papillomavirus (HPV)-positive Head and Neck Squamous Cell Carcinomas
(HNSCC) comprise a particular cancer entity traditionally associated with better clinical …

[HTML][HTML] Cellular hierarchy framework based on single-cell/multi-patient sample sequencing reveals metabolic biomarker PYGL as a therapeutic target for HNSCC

J Guan, X Xu, G Qiu, C He, X Lu, K Wang, X Liu… - Journal of Experimental …, 2023 - Springer
Background A growing body of research has revealed the connection of metabolism
reprogramming and tumor progression, yet how metabolism reprogramming affects inter …

A benchmark for oncologic outcomes and model for lethal recurrence risk after transoral robotic resection of HPV-related oropharyngeal cancers

RM Brody, D Shimunov, RB Cohen, A Lin, JN Lukens… - Oral oncology, 2022 - Elsevier
Objectives Increasing use of transoral robotic surgery (TORS) is likely to impact outcomes for
HPV+ oropharyngeal squamous cell carcinomas (OPSCCs). We aimed to describe …

[HTML][HTML] Identification of immune-related lncRNA signature to predict prognosis and immunotherapeutic efficiency in bladder cancer

L Zhang, L Li, Y Zhan, J Wang, Z Zhu… - Frontiers in Oncology, 2021 - frontiersin.org
Purpose Identify immune-related lncRNA (IRL) signature related to the prognosis and
immunotherapeutic efficiency for bladder cancer (BLCA) patients. Methods A total of 397 …

[HTML][HTML] NF-κB over-activation portends improved outcomes in HPV-associated head and neck cancer

TP Schrank, AC Prince, T Sathe, X Wang, X Liu… - Oncotarget, 2022 - ncbi.nlm.nih.gov
Evolving understanding of head and neck squamous cell carcinoma (HNSCC) is leading to
more specific diagnostic disease classifications. Among HNSCC caused by the human …

[HTML][HTML] HPV16 E6 and E7 oncoproteins stimulate the glutamine pathway maintaining cell proliferation in a SNAT1-dependent fashion

Y Ortiz-Pedraza, JO Muñoz-Bello, LA Ramos-Chávez… - Viruses, 2023 - mdpi.com
Persistent high-risk human papillomavirus infection is the main risk factor for cervical cancer
establishment, where the viral oncogenes E6 and E7 promote a cancerous phenotype …

[HTML][HTML] The intratumor bacterial and fungal microbiome is characterized by hpv, smoking, and alcohol consumption in head and neck squamous cell carcinoma

J Chakladar, D John, S Magesh, M Uzelac… - International Journal of …, 2022 - mdpi.com
Head and neck squamous cell carcinoma (HNSCC) tumor phenotypes and clinical
outcomes are significantly influenced by etiological agents, such as HPV infection, smoking …