MicroRNA‐130a controls bone marrow mesenchymal stem cell differentiation towards the osteoblastic and adipogenic fate

Z Lin, H He, M Wang, J Liang - Cell proliferation, 2019 - Wiley Online Library
Objectives With age, bone marrow mesenchymal stem cells (BMSC) have reduced ability of
differentiating into osteoblasts but have increased ability of differentiating into adipocytes …

[PDF][PDF] Using micro computed tomographic imaging for analyzing kidney stones

JC Williams Jr, JE Lingeman… - Comptes …, 2021 - comptes-rendus.academie-sciences …
Résumé Stone analysis is a critical part of the clinical characterization of urolithiasis. This
article reviews the strengths and limitations of micro CT in the analysis of stones. Using …

Bone hydration: How we can evaluate it, what can it tell us, and is it an effective therapeutic target?

RK Surowiec, MR Allen, JM Wallace - Bone reports, 2022 - Elsevier
Water constitutes roughly a quarter of the cortical bone by volume yet can greatly influence
mechanical properties and tissue quality. There is a growing appreciation for how water can …

Adenine-induced chronic kidney disease induces a similar skeletal phenotype in male and female C57BL/6 mice with more severe deficits in cortical bone properties …

CE Metzger, EA Swallow, AJ Stacy, MR Allen - PLoS One, 2021 - journals.plos.org
Chronic kidney disease (CKD) causes bone loss, particularly in cortical bone, through
formation of cortical pores which lead to skeletal fragility. Animal models of CKD have shown …

Fabrication and characterization of bioinspired nanohydroxyapatite scaffolds with different porosities

AM Castillo-Paz, DF Cañon-Davila… - Ceramics …, 2022 - Elsevier
This study aimed to fabricate and characterize bovine nanohydroxyapatite (nano-HAp)
scaffolds at a low sintering temperature. The compact bone/starch systems were formed …

Strain-specific alterations in the skeletal response to adenine-induced chronic kidney disease are associated with differences in parathyroid hormone levels

CE Metzger, EA Swallow, AJ Stacy, MR Allen - Bone, 2021 - Elsevier
Chronic kidney disease (CKD) leads to loss of cortical bone through cortical thinning and the
development of cortical porosity. The goal of this current study was to assess cortical bone …

Elevations in cortical porosity occur prior to significant rise in serum parathyroid hormone in young female mice with adenine-induced CKD

CE Metzger, EA Swallow, MR Allen - Calcified tissue international, 2020 - Springer
Chronic kidney disease (CKD) leads to significant bone loss primarily through the
development of cortical porosity. In both patients and animal models of CKD, sustained …

Cortical porosity development and progression is mitigated after etelcalcetide treatment in an animal model of chronic kidney disease

EA Swallow, CE Metzger, CL Newman, NX Chen… - Bone, 2022 - Elsevier
Purpose Chronic kidney disease (CKD) leads to increased bone fragility and risk of fracture.
Cortical deteriorations, including cortical porosity, are key factors in fracture susceptibility in …

[HTML][HTML] Cortical porosity occurs at varying degrees throughout the skeleton in rats with chronic kidney disease

CE Metzger, CL Newman, SP Tippen, NT Golemme… - Bone Reports, 2022 - Elsevier
Cortical porosity develops in chronic kidney disease (CKD) and increases with progressing
disease. Cortical porosity is likely a prominent contributor to skeletal fragility/fracture. The …

Longitudinal evolution of bone microarchitecture and bone strength in type 2 diabetic postmenopausal women with and without history of fragility fractures—a 5-year …

U Heilmeier, GB Joseph, C Pasco, N Dinh… - Frontiers in …, 2021 - frontiersin.org
Introduction Diabetic bone disease is characterized by an increased fracture risk which may
be partly attributed to deficits in cortical bone quality such as higher cortical porosity …