More than a simple biomarker: the role of NGAL in cardiovascular and renal diseases

M Buonafine, E Martinez-Martinez, F Jaisser - Clinical science, 2018 - portlandpress.com
Neutrophil gelatinase-associated lipocalin (NGAL) is a small circulating protein that is highly
modulated in a wide variety of pathological situations, making it a useful biomarker of …

Beyond natriuretic peptides for diagnosis and management of heart failure

NE Ibrahim, JL Januzzi Jr - Clinical chemistry, 2017 - academic.oup.com
BACKGROUND Heart failure (HF) is a complex syndrome with an enormous societal burden
in terms of cost and morbidity and mortality. Natriuretic peptide (NP) testing is now widely …

NGAL and MMP-9/NGAL as biomarkers of plaque vulnerability and targets of statins in patients with carotid atherosclerosis

W Eilenberg, S Stojkovic, A Kaider… - Clinical Chemistry and …, 2017 - degruyter.com
Background: Neutrophil gelatinase associated lipocalin (NGAL) is expressed in
atherosclerotic lesions and was recently implicated in the pathogenesis of cardiovascular …

Biomarkers in acute heart failure

A Mallick, JL Januzzi Jr - Revista Española de Cardiología (English Edition), 2015 - Elsevier
The care of patients with acutely decompensated heart failure is being reshaped by the
availability and understanding of several novel and emerging heart failure biomarkers. The …

The future for diagnostic tests of acute kidney injury in critical care: evidence synthesis, care pathway analysis and research prioritisation

PS Hall, ED Mitchell, AF Smith, DA Cairns… - 2018 - research.ed.ac.uk
The future for diagnostic tests of acute kidney injury in critical care: evidence synthesis, care
pathway analysis and research Page 1 Edinburgh Research Explorer The future for diagnostic …

Comparison of neutrophil gelatinase-associated lipocalin versus B-type natriuretic peptide and cystatin C to predict early acute kidney injury and outcome in patients …

A Palazzuoli, G Ruocco, M Pellegrini, C De Gori… - The American journal of …, 2015 - Elsevier
Neutrophil gelatinase–associated lipocalin (NGAL) has been described in chronic heart
failure (HF) as marker of tubular damage and renal dysfunction; however, less data are …

The role of neutrophil gelatinase associated lipocalin (NGAL) as biological constituent linking depression and cardiovascular disease

L Gouweleeuw, PJW Naudé, M Rots… - Brain, behavior, and …, 2015 - Elsevier
Depression is more common in patients with cardiovascular disease than in the general
population. Conversely, depression is a risk factor for developing cardiovascular disease …

Combined biomarker analysis for risk of acute kidney injury in patients with ST-segment elevation myocardial infarction

YC Tung, CH Chang, YC Chen, PH Chu - PloS one, 2015 - journals.plos.org
Background Acute kidney injury (AKI) complicating ST-segment elevation myocardial
infarction (STEMI) increases subsequent morbidity and mortality. We combined the …

Diagnostic and prognostic utility of procalcitonin in patients presenting to the emergency department with dyspnea

GA Alba, QA Truong, HK Gaggin, PU Gandhi… - The American journal of …, 2016 - Elsevier
Background Among patients in the emergency department, dyspnea is a common complaint
and can pose a diagnostic challenge. Biomarkers are used increasingly to improve …

A clinical approach to the acute cardiorenal syndrome

JC Jentzer, LS Chawla - Critical care clinics, 2015 - criticalcare.theclinics.com
The medical community has increasingly recognized the complex relationship between the
heart and kidneys over recent years. The term cardiorenal syndromes (CRSs) encompasses …