Impaired beta‐cell function is a recognized cornerstone of diabetes pathophysiology.
Estimates of insulin secretory capacity are useful to inform clinical practice, helping to …

Type 1 diabetes (T1D) is an autoimmune disease in which the insulin-producing β cells of
the pancreas are destroyed by T lymphocytes. Recent studies have demonstrated that …

Background Janus kinase (JAK) inhibitors, including baricitinib, block cytokine signaling and
are effective disease-modifying treatments for several autoimmune diseases. Whether …

An open-label, first-in-human phase 1/2 study is being conducted to evaluate the safety and
efficacy of pancreatic endoderm cells (PECs) implanted in non-immunoprotective …

Previous studies showed a low-grade enterovirus infection in the pancreatic islets of patients
with newly diagnosed type 1 diabetes (T1D). In the Diabetes Virus Detection (DiViD) …

Regular physical activity improves cardiometabolic and musculoskeletal health, helps with
weight management, improves cognitive and psychosocial functioning, and is associated …

Abstract Purpose of Review Epidemiological research on type 1 diabetes (T1D) has
traditionally focussed on the paediatric age group, but recent data in adults has confirmed it …

Diabetes is a highly heterogeneous condition; yet, it is diagnosed by measuring a single
blood-borne metabolite, glucose, irrespective of aetiology. Although pragmatically helpful …

First envisioned by early diabetes clinicians, a person-centred approach to care was an
aspirational goal that aimed to match insulin therapy to each individual's unique …

Background Diabetes in childhood and adolescence includes autoimmune and non-
autoimmune forms with heterogeneity in clinical and biochemical presentations. An …