Biological molecular motors (or biomolecular motors for short) are nature's solution to the
efficient conversion of chemical energy to mechanical movement. In biological systems …

Nuclear movement within a cell occurs in a variety of eukaryotic organisms including yeasts
and filamentous fungi. Fungal molecular genetic studies identified the minus-end-directed …

Eukaryotic cells use microtubule-based intracellular transport for the delivery of many
subcellular cargos, including organelles. The canonical view of organelle transport is that …

Karl Esser (born 1924) is retired Professor of General Botany and Director of the Botanical
Garden at the Ruhr-Universität Bochum (Germany). His scientific work focused on basic …

Cytoplasmic microtubule arrays play important and diverse roles within fungal cells,
including serving as molecular highways for motor-driven organelle motility. While the …

Nitroquinoline 1-oxide (4-NQO) is a highly carcinogenic chemical that induces mutations in
bacteria, fungi, and animals through the formation of bulky purine adducts. 4-NQO has been …

Eukaryotic cells internalize cargo at the plasma membrane via endocytosis, a vital process
that is accomplished through a complex network of endosomal organelles. In mammalian …

The minus end–directed microtubule motor cytoplasmic dynein transports various cellular
cargoes, including early endosomes, but how dynein binds to its cargo remains unclear …

Microtubule-based distribution of organelles/vesicles is crucial for the function of many types
of eukaryotic cells and the molecular motor cytoplasmic dynein is required for transporting a …

The proper functioning of organelles depends on their intracellular localization, mediated by
motor protein–dependent transport on cytoskeletal tracks. Rather than directly associating …