Type 2 diabetes mellitus (T2DM) is a systemic disease characterized by hyperglycemia,
hyperlipidemia, and organismic insulin resistance. This pathological shift in both circulating …

Mitochondria play a key role in maintaining energy homeostasis in metabolic tissues,
including adipose tissues. The two main types of adipose tissues are the white adipose …

One of the main functions of mitochondria is production of ATP for cellular energy needs,
however, it becomes more recognized that mitochondria are involved in differentiation and …

White adipose tissue is one of the largest organs of the body. It plays a key role in whole‐
body energy status and metabolism; it not only stores excess energy but also secretes …

Oxidative stress in the insulin target tissues has been implicated in the pathophysiology of
type 2 diabetes. The study has examined the oxidative stress parameters in the …

New Findings What is the topic of this review? The review covers basic knowledge about the
role of mitochondria in the homeostatic function of adipose tissue. It also provide a …

Obesity is a major risk factor for several metabolic diseases, including type 2 diabetes,
hyperlipidemia, cardiovascular diseases, and brain disorders. Growing evidence suggests …

We are facing a revival of the strategy to counteract obesity and associated metabolic
disorders by inducing thermogenesis mediated by mitochondrial uncoupling protein-1 …

Adipose tissue is the most important energy storage organ in the body, maintaining its
normal energy metabolism function and playing a vital role in keeping the energy balance of …

Impaired mitochondrial oxidative phosphorylation (OXPHOS) in liver tissue has been
hypothesised to contribute to the development of nonalcoholic steatohepatitis in patients …