The diagnosis and treatment of neurological ailments always remain an utmost challenge for
research fraternity due to the presence of BBB. The intranasal route appeared as an …

Neuroimmune diseases have diverse symptoms and etiologies but all involve pathological
inflammation that affects normal central nervous system signaling. Critically, many …

Background: This review addresses recent advances in the understanding of the
mechanisms that underlie burst release and strategies developed to control burst from poly …

A thermosensitive hydrogel has been prepared with chitosan and αβ-glycerophosphate (αβ-
GP) which could be transited from solution into gel at 37° C. The thermosensitive …

Targeting analgesic drugs for spinal delivery reflects the fact that while the conscious
experience of pain is mediated supraspinally, input initiated by high intensity stimuli, tissue …

Metal–organic frameworks are the new type of crystalline porous materials with specific
properties such as appropriate catalytic activity, accessible surface area, tunable pore …

The high water content and biocompatibility of amino-acid-based supramolecular hydrogels
have generated growing interest in drug delivery research. Nevertheless, the existing …

Research on communication between glia and neurons has increased in the past decade.
The onset of neuropathic pain, a major clinical problem that is not resolved by available …

The GABA B receptor plays an important role in the control of neurotransmitter release, and
experiments using preclinical models have shown that modulation of this receptor can have …

Nanogels based on poly (N-isopropylacrylamide) are attractive vehicles for prolonged
duration local anesthesia because of their tunable size, number of functional groups …