Bone, as a mineralized composite of inorganic (mostly carbonated hydroxyapatite) and
organic (mainly type I collagen) phases, possesses a unique combination of remarkable …

Over the last several years, significant progress has been made toward understanding the
mechanisms involved in the mineralization of hard collagenous tissues, such as bone and …

Objectives Remineralization of demineralized dentin is important for improving dentin
bonding stability and controlling primary and secondary caries. Nevertheless, conventional …

Biomineralization can be considered as nature's strategy to produce and sustain
biominerals, primarily via creation of hard tissues for protection and support. This review …

Curcumin, primary component of the spice turmeric extracted from the rhizomes of Curcuma
longa, represents the major anti-oxidant and anti-inflammatory substance found in turmeric …

In vertebrates and invertebrates, biomineralization is controlled by the cell and the proteins
they produce. A large number of these proteins are intrinsically disordered, gaining some …

More than 300 million years ago, vertebrates emerged from the vast oceans to conquer
gravity and the dry land. With this transition, new adaptations occurred that included …

Synthetic substitutes of bone grafts, such as calcium phosphate–based ceramics, have
shown some good clinical successes in the regeneration of large bone defects and are …

Raine syndrome is caused by mutations in FAM20C, which had been reported to encode a
secreted component of bone and teeth. We found that FAM20C encodes a Golgi-localized …

Dentin sialophosphoprotein (DSPP) and dentin matrix protein-1 (DMP-1) are highly
phosphorylated proteins that belong to the family of small integrin-binding ligand N-linked …