The activating receptor NKG2D is peculiar in its capability to bind to numerous and highly
diversified MHC class I-like self-molecules. These ligands are poorly expressed on normal …

Natural killer (NK) cells are effector cells of the innate immune system and are important in
the control of viral infections. Their relevance is reflected by the multiple mechanisms …

A systematic quantitative analysis of temporal changes in host and viral proteins throughout
the course of a productive infection could provide dynamic insights into virus-host …

MicroRNAs (miRNAs) provide new therapeutic targets for many diseases, while their myriad
roles in development and cellular processes make them fascinating to study. We still do not …

The study of miRNAs started in 1993, when Lee et al. observed their involvement in the
downregulation of a crucial protein known as LIN-14 in the nematode Caenorhabditis …

Human cytomegalovirus (CMV), one of the eight herpesviruses that commonly infect
humans, is best known for its propensity to cause disease in immunocompromised patients …

Breast cancer stem-like cells (BCSC) are crucial for metastasis but the underlying
mechanisms remain elusive. Here, we report that tumor-infiltrating natural killer (NK) cells …

Considerable evidence has been gathered over the last 10 years showing that the tumor
microenvironment (TME) is not simply a passive recipient of immune cells, but an active …

MicroRNAs (miRNAs) are small non-coding RNAs important in gene regulation. They are
able to regulate mRNA translation through base-pair complementarity. Cellular miRNAs …

Cancer is one of the leading causes of death worldwide. Human cytomegalovirus (HCMV), a
well-studied herpesvirus, has been implicated in malignancies derived from breast …