Melatonin as a potential antihypertensive treatment

F Simko, L Paulis - Journal of pineal research, 2007 - Wiley Online Library
The number of patients with well‐controlled hypertension is alarmingly low worldwide and
new approaches to treatment of increased blood pressure (BP) are being sought. Melatonin …

[HTML][HTML] Evidence for the benefits of melatonin in cardiovascular disease

M Tobeiha, A Jafari, S Fadaei, SMA Mirazimi… - Frontiers in …, 2022 - frontiersin.org
The pineal gland is a neuroendocrine gland which produces melatonin, a neuroendocrine
hormone with critical physiological roles in the circadian rhythm and sleep-wake cycle …

Beneficial effects of melatonin on obesity and lipid profile in young Zucker diabetic fatty rats

A Agil, M Navarro‐Alarcón, R Ruiz… - Journal of pineal …, 2011 - Wiley Online Library
The study objective was to investigate the effects of melatonin on obesity and obesity‐
associated systolic hypertension and dyslipidemia in young male Zucker diabetic fatty (ZDF) …

Role of melatonin in metabolic regulation

A Korkmaz, T Topal, DX Tan, RJ Reiter - Reviews in Endocrine and …, 2009 - Springer
Although the human genome has remained unchanged over the last 10,000 years, our
lifestyle has become progressively more divergent from those of our ancient ancestors. This …

[HTML][HTML] Melatonin improves arsenic-induced hypertension through the inactivation of the Sirt1/autophagy pathway in rat

S Balarastaghi, S Barangi, H Hosseinzadeh… - Biomedicine & …, 2022 - Elsevier
Arsenic (As), a metalloid chemical element, is classified as heavy metal. Previous studies
proposed that As induces vascular toxicity by inducing autophagy, apoptosis, and oxidative …

The potential value of natural antioxidative treatment in glaucoma

M Mozaffarieh, MC Grieshaber, S Orgül… - Survey of ophthalmology, 2008 - Elsevier
Glaucomatous optic neuropathy implies loss of retinal ganglion cells, including their axons,
and a major tissue remodeling, especially in the optic nerve head. Although increased …

Melatonin ameliorates endothelial dysfunction, vascular inflammation, and systemic hypertension in rats with chronic intermittent hypoxia

MW Hung, GM Kravtsov, CF Lau… - Journal of pineal …, 2013 - Wiley Online Library
The pathogenesis of hypertension in patients with obstructive sleep apnea (OSA) is
associated with endothelial dysfunction induced by chronic intermittent hypoxia (IH). Studies …

Melatonin and metabolic regulation: a review

M Navarro-Alarcón, FJ Ruiz-Ojeda… - Food & function, 2014 - pubs.rsc.org
Human life expectancy has increased over the past 50 years due to scientific and medical
advances and higher food availability. However, overweight and obesity affect more than …

Melatonin for the management of preeclampsia: a review

A Langston-Cox, SA Marshall, D Lu, KR Palmer… - Antioxidants, 2021 - mdpi.com
Preeclampsia is a disease specific to pregnancy characterised by new-onset hypertension
with maternal organ dysfunction and/or fetal growth restriction. It remains a major cause of …

Antihypertensive and cardioprotective effects of pumpkin seed oil

AEMK El-Mosallamy, AA Sleem… - Journal of Medicinal …, 2012 - liebertpub.com
Pumpkin seed oil is a natural product commonly used in folk medicine for treatment of
prostatic hypertrophy. In the present study, the effects of treatment with pumpkin seed oil on …