[HTML][HTML] Advances in research on bioactivity, toxicity, metabolism, and pharmacokinetics of usnic acid in vitro and in vivo
H Wang, M Xuan, C Huang, C Wang - Molecules, 2022 - mdpi.com
Lichens are among the most widely distributed plants on earth and have the longest growth
cycle. Usnic acid is an abundant characteristic secondary metabolite of lichens and the …
cycle. Usnic acid is an abundant characteristic secondary metabolite of lichens and the …
[HTML][HTML] Linking lichen metabolites to genes: emerging concepts and lessons from molecular biology and metagenomics
G Singh - Journal of Fungi, 2023 - mdpi.com
Lichen secondary metabolites have tremendous pharmaceutical and industrial potential.
Although more than 1000 metabolites have been reported from lichens, less than 10 have …
Although more than 1000 metabolites have been reported from lichens, less than 10 have …
[HTML][HTML] Anti-inflammatory and analgesic potential of leaf extract of Justicia adhatoda L.(Acanthaceae) in Carrageenan and Formalin-induced models by targeting …
A Basit, T Shutian, A Khan, SM Khan… - Biomedicine & …, 2022 - Elsevier
Plants are regarded as a valuable and inexpensive source of new drug development, and a
variety of plant compounds are now being used in clinical trials to treat a variety of ailments …
variety of plant compounds are now being used in clinical trials to treat a variety of ailments …
[HTML][HTML] Depside and depsidone synthesis in lichenized fungi comes into focus through a genome-wide comparison of the olivetoric acid and physodic acid …
Primary biosynthetic enzymes involved in the synthesis of lichen polyphenolic compounds
depsides and depsidones are non-reducing polyketide synthases (NR-PKSs), and …
depsides and depsidones are non-reducing polyketide synthases (NR-PKSs), and …
[HTML][HTML] Is Caperatic Acid the Only Compound Responsible for Activity of Lichen Platismatia glauca within the Nervous System?
E Studzińska-Sroka, A Majchrzak-Celińska… - Antioxidants, 2022 - mdpi.com
Lichens are a source of various biologically active compounds. However, the knowledge
about them is still scarce, and their use in medicine is limited. This study aimed to investigate …
about them is still scarce, and their use in medicine is limited. This study aimed to investigate …
[HTML][HTML] Identification of a lichen depside polyketide synthase gene by heterologous expression in Saccharomyces cerevisiae
JT Kealey, JP Craig, PJ Barr - Metabolic Engineering Communications, 2021 - Elsevier
Lichen-forming fungi produce a variety of secondary metabolites including bioactive
polyketides. Advances in DNA and RNA sequencing have led to a growing database of new …
polyketides. Advances in DNA and RNA sequencing have led to a growing database of new …
[HTML][HTML] Lecanoric acid mediates anti-proliferative effects by an M phase arrest in colon cancer cells
LA Roser, P Erkoc, R Ingelfinger, M Henke… - Biomedicine & …, 2022 - Elsevier
Lichen extracts containing, among other compounds, depsides such as evernic acid,
atranorin, and lecanoric acid possess anti-proliferative effects. We aimed to identify lichen …
atranorin, and lecanoric acid possess anti-proliferative effects. We aimed to identify lichen …
[HTML][HTML] The pharmacological potential of novel melittin variants from the honeybee and solitary bees against inflammation and cancer
The venom of honeybees is composed of numerous peptides and proteins and has been
used for decades as an anti-inflammatory and anti-cancer agent in traditional medicine …
used for decades as an anti-inflammatory and anti-cancer agent in traditional medicine …
[HTML][HTML] Venomics of the milos viper (Macrovipera schweizeri) unveils patterns of venom composition and exochemistry across blunt-nosed viper venoms
Introduction: Snakebite is a neglected tropical disease and a globally important driver of
death and morbidity. Vipers of the genus Macrovipera (Viperidae: Viperinae) are among the …
death and morbidity. Vipers of the genus Macrovipera (Viperidae: Viperinae) are among the …
[HTML][HTML] Methodological aspects of green extraction of usnic acid using natural deep eutectic solvents
M Kulinowska, S Dresler, A Skalska-Kamińska… - Molecules, 2023 - mdpi.com
Usnic acid (UA) is a compound with multiple biological activities that make it useful in
various industries, eg, pharmaceutical, cosmetic, dentistry, and agricultural sectors. Lichens …
various industries, eg, pharmaceutical, cosmetic, dentistry, and agricultural sectors. Lichens …