Regulatory T (Treg) cells suppress inflammation and regulate immune system activity. In
patients with systemic or organ-specific autoimmune diseases or those receiving …

Short-chain fatty acids (SCFAs), as products of intestinal bacterial metabolism, are
particularly relevant in the diagnosis of intestinal dysbiosis. The most common studies of …

Regulatory T (TReg) cells are essential for maintaining peripheral tolerance, preventing
autoimmune diseases and limiting chronic inflammatory diseases. However, they also limit …

The immune system has evolved to mount an effective defense against pathogens and to
minimize deleterious immune-mediated inflammation caused by commensal …

CD4+ T cells are commonly divided into regulatory T (Treg) cells and conventional T helper
(Th) cells. Th cells control adaptive immunity against pathogens and cancer by activating …

Regulatory T cells (Tregs), which are characterized by expression of the transcription factor
Foxp3, are a dynamic and heterogeneous population of cells that control immune responses …

Abnormalities in CD4+ CD25+ Foxp3+ regulatory T (T reg) cells have been implicated in
susceptibility to allergic, autoimmune, and immunoinflammatory conditions. However …

Compelling evidence suggests that Foxp3‐expressing CD25+ CD4+ regulatory T cells
(Treg) are generated within the thymus as a separate lineage. However, Foxp3+ CD4+ Treg …

Foxp3 plays a key role in CD4+ CD25+ Treg cell function in mice and represents a specific
marker for these cells. Despite the strong association between FOXP3 expression and …

The transcription factor FOXP3 is critical for development and function of regulatory T cells
(Treg). Their number and functioning appears to be crucial in the prevention of autoimmunity …