Prognostic significance of serum alkaline phosphatase level in osteosarcoma: a meta‐analysis of published data

HY Ren, LL Sun, HY Li, ZM Ye - BioMed research international, 2015 - Wiley Online Library
Background. Serum alkaline phosphatase (SALP) is commonly elevated in osteosarcoma
patients. A number of studies have investigated the prognostic role of SALP level in patients …

[HTML][HTML] Risk and clinicopathological features of osteosarcoma metastasis to the lung: a population-based study

X Huang, J Zhao, J Bai, H Shen, B Zhang, L Deng… - Journal of bone …, 2019 - Elsevier
Background Osteosarcoma is the most common primary sarcoma of the bone. Lung
osteosarcoma metastases at diagnosis have a significantly poor prognosis, even when …

Autophagy inhibitor enhance ZnPc/BSA nanoparticle induced photodynamic therapy by suppressing PD-L1 expression in osteosarcoma immunotherapy

W Yu, Y Wang, J Zhu, L Jin, B Liu, K Xia, J Wang, J Gao… - Biomaterials, 2019 - Elsevier
Elevated expression of programmed death ligand-1 (PD-L1) on the surface of tumor cells
can exhaust cytotoxic T lymphocyte cells and lead to the failure of anti-tumor immunity …

Systematic review of craniofacial osteosarcoma regarding different clinical, therapeutic and prognostic parameters

V Weber, R Stigler, R Lutz, M Kesting… - Frontiers in …, 2023 - frontiersin.org
Background Osteosarcomas are the most common primary bone tumor while occurrence in
the craniofacial skeleton is relatively rare. There are clinical differences of osteosarcomas …

Prevalence of metastasis at diagnosis of osteosarcoma: an international comparison

TA Marko, BJ Diessner, LG Spector - Pediatric blood & cancer, 2016 - Wiley Online Library
Background Osteosarcoma (OS) is the most common primary malignant bone tumor in many
countries, with metastatic disease responsible for most patient deaths. This study compares …

[PDF][PDF] miR-186-5p functions as a tumor suppressor in human osteosarcoma by targeting FOXK1

Z Zhang, W Zhang, J Mao, Z Xu… - Cell Physiol …, 2019 - cellphysiolbiochem.com
Abstract Background/Aims: Aberrantly expressed miRNAs play a vital role in the
development of some cancers, such as human osteosarcoma (OS). However, the detailed …

[HTML][HTML] Long noncoding RNA LINC01133 functions as an miR-422a sponge to aggravate the tumorigenesis of human osteosarcoma

HF Zeng, HY Qiu, FB Feng - Oncology research, 2018 - ncbi.nlm.nih.gov
Long noncoding RNAs (lncRNAs) have been verified to participate in various types of
malignant tumors, including osteosarcoma (OS), which is the most common primary bone …

Cytotoxic mechanism of PLK1 inhibitor GSK461364 against osteosarcoma: mitotic arrest, apoptosis, cellular senescence, and synergistic effect with paclitaxel

YS Chou, CC Yen, WM Chen… - International …, 2016 - spandidos-publications.com
Abstract Polo-like kinase 1 (PLK1), a serine/threonine kinase and an oncogene, is crucial in
regulating cell cycle progression. PLK1 also has been demonstrated as a potential target of …

Improvement in high-grade osteosarcoma survival: results from 202 patients treated at a single institution in Taiwan

GY Hung, HJ Yen, CC Yen, PK Wu, CF Chen… - Medicine, 2016 - journals.lww.com
Improvement in High-Grade Osteosarcoma Survival: Results fro... : Medicine Improvement in
High-Grade Osteosarcoma Survival: Results from 202 Patients Treated at a Single Institution in …

Bone sarcoma incidence in the Netherlands

LM Goedhart, VKY Ho, PDS Dijkstra… - Cancer …, 2019 - Elsevier
Abstract Aims Chondrosarcoma, osteosarcoma and Ewing sarcoma form the majority of
malignant primary tumours of bone. High-grade bone sarcomas require intensive treatment …