[HTML][HTML] Ferroptosis: a cell death connecting oxidative stress, inflammation and cardiovascular diseases

Y Yu, Y Yan, F Niu, Y Wang, X Chen, G Su, Y Liu… - Cell death …, 2021 - nature.com
Ferroptosis, a recently identified and iron-dependent cell death, differs from other cell death
such as apoptosis, necroptosis, pyroptosis, and autophagy-dependent cell death. This form …

[HTML][HTML] The molecular mechanisms of ferroptosis and its role in cardiovascular disease

Y Zhang, L Xin, M Xiang, C Shang, Y Wang… - Biomedicine & …, 2022 - Elsevier
Ferroptosis is a programmed iron-dependent cell death characterized by accumulation of
lipid peroxides (LOOH) and redox disequilibrium. Ferroptosis shows unique characteristics …

[HTML][HTML] The molecular mechanisms of iron metabolism and its role in cardiac dysfunction and cardioprotection

T Ravingerová, L Kindernay, M Barteková… - International journal of …, 2020 - mdpi.com
Iron is an essential mineral participating in different functions of the organism under
physiological conditions. Numerous biological processes, such as oxygen and lipid …

Iron metabolism in cardiovascular disease: physiology, mechanisms, and therapeutic targets

KT Sawicki, A De Jesus, H Ardehali - Circulation research, 2023 - Am Heart Assoc
The cardiovascular system requires iron to maintain its high energy demands and metabolic
activity. Iron plays a critical role in oxygen transport and storage, mitochondrial function, and …

The clinical implications of endothelial dysfunction

ME Widlansky, N Gokce, JF Keaney, JA Vita - Journal of the American …, 2003 - jacc.org
Defining new approaches for the prevention and treatment of atherosclerosis is an important
priority. Recently, measurement of endothelial function in patients has emerged as a useful …

[图书][B] Oxidation and antioxidants in organic chemistry and biology

ET Denisov, IB Afanas' ev - 2005 - taylorfrancis.com
Providing a comprehensive review of reactions of oxidation for different classes of organic
compounds and polymers, and biological processes mediated by free radicals, Oxidation …

Absorption and metabolism of polyphenols in the gut and impact on health

A Scalbert, C Morand, C Manach, C Rémésy - Biomedicine & …, 2002 - Elsevier
Polyphenols are the most abundant antioxidants in the human diet. They show a
considerable structural diversity, which largely influences their bioavailability. Phenolic acids …

Cross-talk between iron metabolism and diabetes

JM Fernández-Real, A López-Bermejo, W Ricart - Diabetes, 2002 - Am Diabetes Assoc
Emerging scientific evidence has disclosed unsuspected influences between iron
metabolism and type 2 diabetes. The relationship is bi-directional—iron affects glucose …

[HTML][HTML] Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative …

DB Kell - BMC medical genomics, 2009 - Springer
Background The production of peroxide and superoxide is an inevitable consequence of
aerobic metabolism, and while these particular'reactive oxygen species'(ROSs) can exhibit a …

Anemia as a risk factor for cardiovascular disease in The Atherosclerosis Risk in Communities (ARIC) study

MJ Sarnak, H Tighiouart, G Manjunath… - Journal of the American …, 2002 - jacc.org
Objectives: We investigated whether the presence of anemia is a risk factor for
cardiovascular disease (CVD) outcomes in the general population. Background: Chronic …