Critical review of biodegradable and bioactive polymer composites for bone tissue engineering and drug delivery applications

S Sharma, P Sudhakara, J Singh, RA Ilyas… - Polymers, 2021 - mdpi.com
In the determination of the bioavailability of drugs administered orally, the drugs' solubility
and permeability play a crucial role. For absorption of drug molecules and production of a …

Implantable antimicrobial biomaterials for local drug delivery in bone infection models

JD Caplin, AJ García - Acta biomaterialia, 2019 - Elsevier
Increased use of implantable biomedical devices demonstrates their potential in treating a
wide variety of ailments and disorders in bone trauma and orthopaedic, reconstructive, and …

Sustained release of amoxicillin from hydroxyapatite nanocomposite for bone infections

APS Prasanna, GD Venkatasubbu - Progress in biomaterials, 2018 - Springer
Hydroxyapatite (HAP) is the main constituent of human bone and teeth. Hydroxyapatite
nanoparticles are used for the treatment of various bone infections. Nanohydroxyapatite is a …

Antibiotic and chemotherapeutic enhanced three-dimensional printer filaments and constructs for biomedical applications

JA Weisman, JC Nicholson, K Tappa… - International journal …, 2015 - Taylor & Francis
Three-dimensional (3D) printing and additive manufacturing holds potential for highly
personalized medicine, and its introduction into clinical medicine will have many …

Antibacterial and osteogenic dual-functional micronano composite scaffold fabricated via melt electrowriting and solution electrospinning for bone tissue engineering

X Lai, J Huang, S Huang, J Wang… - … Applied Materials & …, 2024 - ACS Publications
The utilization of micronano composite scaffolds has been extensively demonstrated to
confer the superior advantages in bone repair compared to single nano-or micron-sized …

Tuning the toughness, strength, and biological properties of functionally graded alumina/titania-based composites for use in bone repair applications

RA Youness, SEA Sawan, AR Wassel, AA Ward… - Ceramics …, 2024 - Elsevier
In this study, functionally graded composite (FGC) was prepared using a high-energy ball
mill by fabricating five layers of alumina (Al 2 O 3), titania (TiO 2), hydroxyapatite (HA), and …

Applications of polymeric composites in bone tissue engineering and jawbone regeneration

O Fraile-Martínez, C García-Montero, A Coca… - Polymers, 2021 - mdpi.com
Polymer-based composites are a group of biomaterials that exert synergic and combined
activity. There are multiple reported uses of these composites in multiple biomedical areas …

Coatings and surface modifications imparting antimicrobial activity to orthopedic implants

R Kargupta, S Bok, CM Darr, BD Crist… - Wiley …, 2014 - Wiley Online Library
Bacterial colonization and biofilm formation on an orthopedic implant surface is one of the
worst possible outcomes of orthopedic intervention in terms of both patient prognosis and …

Review on surface treatment for implant infection via gentamicin and antibiotic releasing coatings

A Tiwari, P Sharma, B Vishwamitra, G Singh - Coatings, 2021 - mdpi.com
Surface treatment of metallic implants plays a crucial role in orthopedics and orthodontics.
Metallic implants produce side-effects such as physical, chemical/electro-chemical …

Preparation of gentamicin sulfate eluting fiber mats by emulsion and by suspension electrospinning

P Coimbra, JP Freitas, T Gonçalves, MH Gil… - Materials Science and …, 2019 - Elsevier
This work investigates the immobilization of the antibiotic gentamicin sulfate (GS) in
electrospun fiber mats composed of poly (lactic acid)(PLA), poly (ε-caprolactone)(PCL) and …