[HTML][HTML] The biochemistry and function of pannexin channels
Three family members compose the pannexin family of channel-forming glycoproteins
(Panx1, Panx2 and Panx3). Their primary function is defined by their capacity to form single …
(Panx1, Panx2 and Panx3). Their primary function is defined by their capacity to form single …
Diverse evolutionary paths to cell adhesion
M Abedin, N King - Trends in cell biology, 2010 - cell.com
The morphological diversity of animals, fungi, plants, and other multicellular organisms
stems from the fact that each lineage acquired multicellularity independently. A prerequisite …
stems from the fact that each lineage acquired multicellularity independently. A prerequisite …
Pannexin-1 is required for ATP release during apoptosis but not for inflammasome activation
Y Qu, S Misaghi, K Newton, LL Gilmour… - The Journal of …, 2011 - journals.aai.org
Apoptotic cell death is important for embryonic development, immune cell homeostasis, and
pathogen elimination. Innate immune cells also undergo a very rapid form of cell death …
pathogen elimination. Innate immune cells also undergo a very rapid form of cell death …
Nanoparticles can cause DNA damage across a cellular barrier
G Bhabra, A Sood, B Fisher, L Cartwright… - Nature …, 2009 - nature.com
The increasing use of nanoparticles in medicine has raised concerns over their ability to
gain access to privileged sites in the body. Here, we show that cobalt–chromium …
gain access to privileged sites in the body. Here, we show that cobalt–chromium …
Amyloid β-induced death in neurons involves glial and neuronal hemichannels
JA Orellana, KF Shoji, V Abudara, P Ezan… - Journal of …, 2011 - Soc Neuroscience
The mechanisms involved in Alzheimer's disease are not completely understood and how
glial cells contribute to this neurodegenerative disease remains to be elucidated. Because …
glial cells contribute to this neurodegenerative disease remains to be elucidated. Because …
ATP release through connexin hemichannels and gap junction transfer of second messengers propagate Ca2+ signals across the inner ear
F Anselmi, VH Hernandez, G Crispino… - Proceedings of the …, 2008 - National Acad Sciences
Extracellular ATP controls various signaling systems including propagation of intercellular
Ca2+ signals (ICS). Connexin hemichannels, P2x7 receptors (P2x7Rs), pannexin channels …
Ca2+ signals (ICS). Connexin hemichannels, P2x7 receptors (P2x7Rs), pannexin channels …
Biological role of connexin intercellular channels and hemichannels
R Kar, N Batra, MA Riquelme, JX Jiang - Archives of biochemistry and …, 2012 - Elsevier
Gap junctions (GJ) and hemichannels (HC) formed from the protein subunits called
connexins are transmembrane conduits for the exchange of small molecules and ions …
connexins are transmembrane conduits for the exchange of small molecules and ions …
Connexins: a myriad of functions extending beyond assembly of gap junction channels
HA Dbouk, RM Mroue, ME El-Sabban… - Cell Communication and …, 2009 - Springer
Connexins constitute a large family of trans-membrane proteins that allow intercellular
communication and the transfer of ions and small signaling molecules between cells …
communication and the transfer of ions and small signaling molecules between cells …
Lens gap junctions in growth, differentiation, and homeostasis
The cells of most mammalian organs are connected by groups of cell-to-cell channels called
gap junctions. Gap junction channels are made from the connexin (Cx) family of proteins …
gap junctions. Gap junction channels are made from the connexin (Cx) family of proteins …
Ion channels and signaling in the pituitary gland
Endocrine pituitary cells are neuronlike; they express numerous voltage-gated sodium,
calcium, potassium, and chloride channels and fire action potentials spontaneously …
calcium, potassium, and chloride channels and fire action potentials spontaneously …