Advances in understanding the pathophysiology of lacunar stroke: a review

RW Regenhardt, AS Das, EH Lo, LR Caplan - JAMA neurology, 2018 - jamanetwork.com
Importance Stroke is the second leading cause of death in the world, and nearly one-third of
ischemic strokes are lacunar strokes (LSs) or small subcortical infarcts. Although smaller in …

A population neuroscience approach to the study of cerebral small vessel disease in midlife and late life: an invited review

DR Jorgensen, CE Shaaban… - American Journal …, 2018 - journals.physiology.org
Aging in later life engenders numerous changes to the cerebral microvasculature. Such
changes can remain clinically silent but are associated with greater risk for negative health …

Evaluation of white matter hypodensities on computed tomography in stroke patients using the Fazekas score

S Rudilosso, L San Román, J Blasco… - Clinical Imaging, 2017 - Elsevier
Purpose To assess the reliability of the Fazekas score on brain CT in acute stroke patients.
Methods Two raters evaluated the Fazekas score in 157 CT scans from consecutive patients …

Cerebrovascular disease: Neuroimaging of cerebral small vessel disease

CE Shaaban, DR Jorgensen, PJ Gianaros… - Progress in Molecular …, 2019 - Elsevier
The cerebral microvasculature is exceptionally vulnerable to changes due to aging. Both the
radiological and clinical manifestations of cerebral small vessel disease (cSVD) in older age …

Endothelium and oxidative stress: the Pandora's box of cerebral (and non-only) small vessel disease?

M Maccarrone, L Ulivi, N Giannini… - Current Molecular …, 2017 - ingentaconnect.com
Common cerebral small vessel disease (cSVD) abnormalities are a common
neuroradiological finding, especially in the elderly. They are associated with a wide clinical …

[HTML][HTML] Advances in Lacunar Stroke Pathophysiology: A Review

RW Regenhardt, AS Das, EH Lo, LR Caplan - JAMA neurology, 2018 - ncbi.nlm.nih.gov
Importance: As the second leading cause of death in the world, stroke has a large societal
impact. Nearly one-third of ischemic strokes are lacunar strokes (LS), or small subcortical …

[PDF][PDF] Aspirin against atherosclerotic intracranial arterial stenosis

H Rafael - J Neurol Neurophysiol, 2016 - researchgate.net
There is no doubt that atherosclerosis is a chronic inflammatory disease in the inner wall of
the arteries caused by the laws of hydrodynamics and environmental chemicals present into …

Associations of Oxidative Phosphorylation–Related Genes With Deep Intracerebral Hemorrhage in Taiwan

YC Chen, CM Chen, YS Lee… - Journal of Experimental …, 2018 - journals.sagepub.com
Background: Pathway analysis demonstrated associations between deep intracerebral
hemorrhage (DICH) and the genetic risk score of complex IV of the oxidative …

A population neuroscience approach to the study of cerebral small vessel disease in mid-and late-1

DR Jorgensen, CE Shaaban, CA Wiley, PJ Gianaros… - journals.physiology.org
Aging in later life engenders numerous changes to the cerebral microvasculature. Such
changes can 28 remain clinically silent, but are associated with greater risk for negative …

Genetics of small vessel disease

R Malik - Stroke Genetics, 2017 - Springer
Cerebral 'small vessel disease'(cSVD) refers to a mixture of clinical, cognitive,
neuroimaging, and neuropathologic abnormalities that arise from different pathologic …