Over the past decade, various liquid biopsy techniques have emerged as viable alternatives
to the analysis of traditional tissue biopsy samples. Such surrogate 'biopsies' offer numerous …

Background There is an extensive literature highlighting the utility of blood-based liquid
biopsies in several extracranial tumors for diagnosis and monitoring. Methods The RANO …

Diffuse midline glioma (DMG), formerly called diffuse intrinsic pontine glioma (DIPG), is a
high-grade malignant pediatric brain tumor with a near-zero survival rate. To date, only …

Liquid biopsies have emerged as a minimally invasive cancer detection and monitoring
method, which could identify cancer-related alterations in nucleosome or histone levels and …

Simple Summary Glioblastoma is a highly aggressive brain cancer, and early detection and
accurate diagnosis are crucial for effective treatment. Traditional diagnostic methods have …

Diffuse midline glioma (DMG) is the leading cause of brain tumor-related deaths in children.
DMG typically presents with variable neurologic symptoms between ages 3 and 10 …

Recent insights into histopathological and molecular subgroups of glioma have
revolutionized the field of neuro-oncology by refining diagnostic categories. An emblematic …

Gliomas comprise the most frequent primary central nervous system (CNS) tumors,
characterized by remarkable genetic and epigenetic heterogeneity, difficulty in monitoring …

While immunotherapy for pediatric cancer has made great strides in recent decades,
including the FDA approval of agents such as dinutuximab and tisgenlecleucel, these …

Gliomas are tumors derived from mutations in glial brain cells. Gliomas cause significant
morbidity and mortality and development of precision diagnostics and novel targeted …