Over evolutionary time, the dynamic nature of a genome is driven, in part, by the activity of
transposable elements (TE) such as retrotransposons. On a shorter time scale it has been …

The Genome 10K Project was established in 2009 by a consortium of biologists and
genome scientists determined to facilitate the sequencing and analysis of the complete …

Studying tissue composition and function in non-human primates (NHPs) is crucial to
understand the nature of our own species. Here we present a large-scale cell transcriptomic …

The Ensembl gene annotation system has been used to annotate over 70 different
vertebrate species across a wide range of genome projects. Furthermore, it generates the …

The multispecies coalescent provides a natural framework for accommodating ancestral
genetic polymorphism and coalescent processes that can cause different genomic regions …

Comparative analysis of primate genomes within a phylogenetic context is essential for
understanding the evolution of human genetic architecture and primate diversity. We present …

This unit describes how to use the genome annotation and curation tools MAKER and
MAKER‐P to annotate protein‐coding and noncoding RNA genes in newly assembled …

Speciation events often occur in rapid bursts of diversification, but the ecological and genetic
factors that promote these radiations are still much debated. Using whole transcriptomes …

Six extant species of non-human great apes are currently recognized: Sumatran and
Bornean orangutans, eastern and western gorillas, and chimpanzees and bonobos [1] …

Apes possess two sex chromosomes—the male-specific Y chromosome and the X
chromosome, which is present in both males and females. The Y chromosome is crucial for …