Increasing the sensitivity and accuracy of detecting exosomes as biomarkers for cancer monitoring using optical nanobiosensors

S Yasamineh, N Nikben, M Hamed Ahmed… - Cancer Cell …, 2024 - Springer
The advancement of nanoscience and material design in recent times has facilitated the
creation of point-of-care devices for cancer diagnosis and biomolecule sensing. Exosomes …

Machine Learning-Assisted High-Throughput Identification and Quantification of Protein Biomarkers with Printed Heterochains

X Pan, Z Zhang, Y Yun, X Zhang, Y Sun… - Journal of the …, 2024 - ACS Publications
Advanced in vitro diagnosis technologies are highly desirable in early detection, prognosis,
and progression monitoring of diseases. Here, we engineer a multiplex protein biosensing …

Biosensor-Enhanced Organ-on-a-Chip Models for Investigating Glioblastoma Tumor Microenvironment Dynamics

G Thenuwara, B Javed, B Singh, F Tian - Sensors, 2024 - mdpi.com
Glioblastoma, an aggressive primary brain tumor, poses a significant challenge owing to its
dynamic and intricate tumor microenvironment. This review investigates the innovative …

Single‐Cell Isolation Chip Integrated with Multicolor Barcode Array for High‐Throughput Single‐Cell Exosome Profiling in Tissue Samples

C Wang, Y Zhang, J Wang, Y Han, Y Wang… - Advanced …, 2024 - Wiley Online Library
Exosomes, functional biomarkers involved in cancer progression, have gained widespread
attention for promoting tumor formation, growth, and metastasis. Current bulk exosome …

Metamaterials-tuned light-matter resonance for ultra-sensitivity biological diagnosis

Z Tan, M Su, Y Song - Matter, 2024 - cell.com
Metamaterials exhibit unprecedented flexibility in controlling electromagnetic waves and
support a richer range of resonance modes, which offer superior sensitivity, ease of …

Microdroplet-enhanced chip platform for high-throughput immunotherapy marker screening from extracellular vesicle RNAs and membrane proteins

C Tang, Z Dong, S Yan, B Liu, Z Wang, L Cheng… - Biosensors and …, 2025 - Elsevier
Extracellular vesicles (EVs) are considered as promising candidates for predicting patients
who respond to immunotherapy. Nevertheless, simultaneous detection of multiple EVs …

Simultaneous and multiplexed phenotyping of circulating exosomes with the orthogonal CRISPR–Cas platform

G Su, M Xu, Y Zhu, Y Zhang, Y Lin, Y Yu - Chemical Communications, 2024 - pubs.rsc.org
Simultaneous and multiplexed exosome protein profiling via an orthogonal CRISPR–Cas
platform was achieved in this work. Aptamers were recruited to translate exosome surface …

[PDF][PDF] Colloidal self-assembly in biosensing strategies for biomarkers diagnosis

X Pan, Z Zhang, M Su - The Innovation Materials, 2024 - the-innovation.org
Rapid and high-throughput detection of biomarkers plays an important role in disease
diagnosis, prognosis, and monitoring treatment. Existing diagnostic tools that rely on genetic …

Research on the efficient preparation method of metal-enhanced fluorescent composite structure microarray chip

H Hu, S Kim, X Lu - 2024 International Conference on …, 2024 - spiedigitallibrary.org
Microarray chip with micro-nano composite structure consists of an array of micropost
structures and nanorods covering the top of the posts. This structure can significantly …