Aptamer–protein interactions: from regulation to biomolecular detection

C Ji, J Wei, L Zhang, X Hou, J Tan, Q Yuan… - Chemical …, 2023 - ACS Publications
Serving as the basis of cell life, interactions between nucleic acids and proteins play
essential roles in fundamental cellular processes. Aptamers are unique single-stranded …

Energy transfer with semiconductor quantum dot bioconjugates: a versatile platform for biosensing, energy harvesting, and other developing applications

N Hildebrandt, CM Spillmann, WR Algar, T Pons… - Chemical …, 2017 - ACS Publications
Luminescent semiconductor quantum dots (QDs) are one of the more popular nanomaterials
currently utilized within biological applications. However, what is not widely appreciated is …

Rationally engineered nucleic acid architectures for biosensing applications

M Xiao, W Lai, T Man, B Chang, L Li… - Chemical …, 2019 - ACS Publications
Development of biosensing platforms plays a key role in research settings for identification
of biomarkers and in clinical applications for diagnostics. Biosensors based on nucleic acids …

Aptamer-based nanobiosensors

YS Kim, NHA Raston, MB Gu - Biosensors and Bioelectronics, 2016 - Elsevier
It has been more than two decades since aptamer and the systematic evolution of ligands by
exponential enrichment (SELEX) method were discovered by Larry Gold and Andrew …

[HTML][HTML] Aptamers used for biosensors and targeted therapy

Y Ning, J Hu, F Lu - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Aptamers are single-stranded nucleic acid sequences that can bind to target molecules with
high selectivity and affinity. Most aptamers are screened in vitro by a combinatorial biology …

Nanotechnology-Enhanced No-Wash Biosensors for in Vitro Diagnostics of Cancer

X Huang, Y Liu, B Yung, Y Xiong, X Chen - ACS nano, 2017 - ACS Publications
In vitro biosensors have been an integral component for early diagnosis of cancer in the
clinic. Among them, no-wash biosensors, which only depend on the simple mixing of the …

DNA-mediated homogeneous binding assays for nucleic acids and proteins

H Zhang, F Li, B Dever, XF Li, XC Le - Chemical reviews, 2013 - ACS Publications
The detection of nucleic acids and proteins is fundamental for studying their functions and
for the development of molecular diagnostics. These molecules carry out most biological …

Nanoparticle based fluorescence resonance energy transfer (FRET) for biosensing applications

J Shi, F Tian, J Lyu, M Yang - Journal of materials chemistry B, 2015 - pubs.rsc.org
In the past few decades, Förster resonance energy transfer (FRET) has been used as a
powerful tool for providing nanoscale information in many biosensing and bioanalysis …

Semiconductor quantum dots in chemical sensors and biosensors

MF Frasco, N Chaniotakis - Sensors, 2009 - mdpi.com
Quantum dots are nanometre-scale semiconductor crystals with unique optical properties
that are advantageous for the development of novel chemical sensors and biosensors. The …

Aptamer nanomedicine for cancer therapeutics: barriers and potential for translation

YH Lao, KKL Phua, KW Leong - ACS nano, 2015 - ACS Publications
Aptamer nanomedicine, including therapeutic aptamers and aptamer nanocomplexes, is
beginning to fulfill its potential in both clinical trials and preclinical studies. Especially in …