Most insecticides used against pests and vectors of human disease (eg fleas, flies and
mosquitoes) are spin-offs from agrochemical research and development. The arsenal of safe …

Background Intermittent preventive treatment (IPT) is a promising strategy for malaria control
in infants. We undertook a pooled analysis of the safety and efficacy of IPT in infants (IPTi) …

Priorities among the infectious diseases affecting the three billion people in the less
developed world have been based on prevalence, morbidity, mortality and feasibility of …

Acute kidney injury (AKI) is a fatal medical episode caused by sudden kidney damage or
failure, leading to the death of patients within a few hours or days. Previous studies …

Thromboplastins vary in their sensitivity to the haemostatic defect induced by oral
anticoagulants. To provide a means of standardising prothrombin time tests, the World …

Genetic variation allows the malaria parasite Plasmodium falciparum to overcome
chemotherapeutic agents, vaccines and vector control strategies and remain a leading …

Background: Opioid abuse has increased at an alarming rate. However, available evidence
suggests a wide variance in the use of opioids, as documented by different medical …

Background Oral cholera vaccines consisting of killed whole cells have been available for
many years, but they have not been used extensively in populations with endemic disease …

Antimalarial drugs such as chloroquine are believed to act by inhibiting hemozoin formation
in the food vacuole of the malaria parasite. We have developed a new assay for measuring …

We derive and analyse a deterministic model for the transmission of malaria disease with
mass action form of infection. Firstly, we calculate the basic reproduction number, R0, and …