Background The burden of malaria infection in sub-Saharan Africa among school-aged
children aged 5–15 years is underappreciated and represents an important source of …

Mosquito-borne diseases are a major burden on human health worldwide and their
eradication through vector control methods remains challenging. In particular, the success of …

Background Symptomatic malaria cases reflect only a small proportion of all Plasmodium
spp infections. Many infected individuals are asymptomatic, and persistent asymptomatic …

The temperature-dependence of many important mosquito-borne diseases has never been
quantified. These relationships are critical for understanding current distributions and …

The dry season is a major challenge for Plasmodium falciparum parasites in many malaria
endemic regions, where water availability limits mosquito vectors to only part of the year …

Malaria infections occurring below the limit of detection of standard diagnostics are common
in all endemic settings. However, key questions remain surrounding their contribution to …

Proposed genetic approaches for reducing human malaria include population modification,
which introduces genes into vector mosquitoes to reduce or prevent parasite transmission …

The antimalarial efficacy of the most important vector control interventions—long-lasting
insecticidal nets (LLINs) and indoor residual spraying (IRS)—primarily protect against …

Abstract Background The majority of Plasmodium vivax and Plasmodium falciparum
infections in low-endemic settings are asymptomatic. The relative contribution to the …

Summary Background Potentially untreatable Plasmodium falciparum malaria threatens the
Greater Mekong subregion. A previous series of pilot projects in Myanmar, Laos, Cambodia …