Predictive values of neutrophil-to-lymphocyte ratio on disease severity and mortality in COVID-19 patients: a systematic review and meta-analysis

X Li, C Liu, Z Mao, M Xiao, L Wang, S Qi, F Zhou - Critical Care, 2020 - Springer
Abstract Background Coronavirus disease 2019 (COVID-19), a highly infectious disease,
has been rapidly spreading all over the world and remains a great threat to global public …

Neutrophil-to-lymphocyte ratio and mortality in the United States general population

M Song, BI Graubard, CS Rabkin, EA Engels - Scientific reports, 2021 - nature.com
The neutrophil-to-lymphocyte ratio (NLR) in peripheral blood reflects the balance between
systemic inflammation and immunity and is emerging as a prognostic biomarker in many …

Neutrophils as emerging protagonists and targets in chronic inflammatory diseases

K Rawat, A Shrivastava - Inflammation Research, 2022 - Springer
Introduction Neutrophils are the key cells of our innate immune system with a primary role in
host defense. They rapidly arrive at the site of infection and display a range of effector …

Improved precision of epigenetic clock estimates across tissues and its implication for biological ageing

Q Zhang, CL Vallerga, RM Walker, T Lin, AK Henders… - Genome medicine, 2019 - Springer
Background DNA methylation changes with age. Chronological age predictors built from
DNA methylation are termed 'epigenetic clocks'. The deviation of predicted age from the …

Whole genome sequence analysis of the plasma proteome in black adults provides novel insights into cardiovascular disease

DH Katz, UA Tahir, AG Bick, A Pampana, D Ngo… - Circulation, 2022 - Am Heart Assoc
Background: Plasma proteins are critical mediators of cardiovascular processes and are the
targets of many drugs. Previous efforts to characterize the genetic architecture of the plasma …

Risk stratification for the prognosis of patients with chemoresistant urothelial cancer treated with pembrolizumab

T Kobayashi, K Ito, T Kojima, M Kato, S Kanda… - Cancer …, 2021 - Wiley Online Library
The use of immune checkpoint inhibitors to treat urothelial carcinoma (UC) is increasing
rapidly without clear guidance for validated risk stratification. This multicenter retrospective …

Dynamic status of SII and SIRI alters the risk of cardiovascular diseases: evidence from kailuan cohort study

J Li, D He, J Yu, S Chen, Q Wu, Z Cheng… - Journal of …, 2023 - Taylor & Francis
Background Two novel systemic inflammation indices, SII and SIRI, are associated with
increased risk of cardiovascular diseases (CVD). However, SII and SIRI are prone to change …

Neutrophil‐to‐lymphocyte ratio and outcomes in patients with new‐onset or worsening heart failure with reduced and preserved ejection fraction

FM Curran, U Bhalraam, M Mohan, JS Singh… - ESC heart …, 2021 - Wiley Online Library
Aims Inflammation is thought to play a role in heart failure (HF) pathophysiology. Neutrophil‐
to‐lymphocyte ratio (NLR) is a simple, routinely available measure of inflammation. Its …

Neutrophil-lymphocyte ratio in patients with acute heart failure predicts in-hospital and long-term mortality

JH Cho, HJ Cho, HY Lee, YJ Ki, ES Jeon… - Journal of clinical …, 2020 - mdpi.com
The application of a simple blood test to predict prognosis in acute heart failure (AHF)
patients is not well established. Neutrophil-lymphocyte ratio (NLR) is inexpensive and easy …

Association of the systemic immune-inflammation index with outcomes in acute coronary syndrome patients with chronic kidney disease

S Shi, S Kong, W Ni, Y Lu, J Li, Y Huang… - Journal of …, 2023 - Taylor & Francis
Background The systemic immune-inflammation index (SII; neutrophil× platelet/lymphocyte)
is a novel marker for immune and inflammatory status and is associated with adverse …