Obesity associated with systemic inflammation induces insulin resistance (IR), with
consequent chronic hyperglycemia. A series of reactions are involved in this process …

Early diagnosis and treatment of Alzheimer's Disease (AD) ultimately will require
identification of its pathogenic mechanism. Such a mechanism must explain the hallmark of …

Background: Exercise can ameliorate type II diabetes mellitus (T2DM) by regulating
intestinal flora metabolites. However, the detailed mechanism needs to be further explored …

Neuroanatomical studies of brains from schizophrenic patients report evidence for neuronal
dystrophy, while in genetic studies in schizophrenia there is evidence for mutations in …

Despite the increasing use of protoplasts in plant biotechnology research, shoot
regeneration from protoplasts remains challenging. In this study, we investigated the factors …

Purpose To evaluate the effects of intensity of exercise on insulin resistance and the
expression of inflammatory proteins in the skeletal muscle of diet-induced obese (DIO) rats …

The insulin resistance associated with aging is improved by exercise, but the molecular
mechanisms of this improvement are not fully understood. We investigated whether the …

Protein hepatocyte nuclear factor 4α (HNF‐4α) is atypically activated in the liver of diabetic
rodents and contributes to hepatic glucose production. HNF‐4α and Foxo1 can physically …

Objectives Physical activity has been well known to benefit heart function. The improved
autonomic nervous activity is considered to be mainly responsible for this beneficial effect …

Background Physical exercise improves glucose metabolism and insulin sensitivity. Brain-
derived neurotrophic factor (BDNF) enhances insulin activity in diabetic rodents. Because …