Years of important research has revealed that cells heavily invest in regulating their size.
Nevertheless, it has remained unclear why accurate size control is so important. Our recent …

Directed cell migration is an essential building block of life, present when an embryo
develops, a dendritic cell migrates toward a lymphatic vessel, or a fibrotic organ fails to …

The ability of cells to regulate their shape and volume is critical for many cell functions. How
endocytosis and exocytosis, as important ways of membrane trafficking, affect cellular …

Mechanomimetic materials are particularly attractive for modeling in vitro fibroblast to
myofibroblast (Myof) transition, a key process in the physiological repair of damaged tissue …

Soft‐hard tissue interfaces are widespread in the human body, where matrix stiffness
gradient at the cellular scale is a typical biophysical cue that cells experience. However …

Rigidity of the extracellular matrix markedly regulates many cellular processes. However,
how cells detect and respond to matrix rigidity remains incompletely understood. Here, we …

Cell migration is controlled by the coordinated action of cell adhesion, cytoskeletal
dynamics, contractility and cell extrinsic cues. Integrins are the main adhesion receptors to …

Living cells display various directed motility in response to rigidity gradients of extracellular
matrix. Some cells move preferentially toward stiff matrix (durotaxis), while some cells move …

Bacterial infections in wounds significantly impair the healing process. The use of natural
antibacterial products over synthetic antibiotics has emerged as a new trend to address …

Bone nodule formation by differentiating osteoblasts is considered an in vitro model that
mimics bone modeling. However, the details of osteoblast behavior and matrix production …