In tribology, a considerable number of computational and experimental approaches to
understand the interfacial characteristics of material surfaces in motion and tribological …

Protein glycosylation, the attachment of sugars to amino acid side chains, can endow
proteins with a wide variety of properties of great interest to the engineering biology …

Mucins represent a largely untapped class of polymeric building block for biomaterials,
therapeutics, and other biotechnology. Because the mucin polymer backbone is genetically …

Mucins and mucin-like molecules are highly O-glycosylated proteins present on the cell
surface of mammals and other organisms. These glycoproteins are highly diverse in the …

The functions of secreted animal mucuses are remarkably diverse and include lubricants,
wet adhesives, protective barriers, and mineralizing agents. Although present in all animals …

Articular cartilage is one of the most unique materials found in nature. This tissue's ability to
provide low friction and low wear over decades of constant use is not surpassed, as of yet …

Joint kinematic instability, arising from congenital or acquired musculoskeletal
pathoanatomy or from imbalances in anabolism and catabolism induced by …

Dry eye disease (DED) has high personal and societal costs, but its pathology remains
elusive due to intertwined biophysical and biochemical processes at the ocular surface …

Lubricin, a lubricating glycoprotein abundant in synovial fluid, forms a low-friction brush
polymer interface in tissues exposed to sliding motion including joints, tendon sheaths, and …

We report how the tribological properties of a class of diblock copolymers with architecture
and function inspired by the lubricating glycoprotein lubricin correlate to chemical …