Regulation and function of immediate-early genes in the brain: beyond neuronal activity markers
H Okuno - Neuroscience research, 2011 - Elsevier
Long lasting forms of synaptic plasticity and long-term memory formation require new mRNA
and protein synthesis. While activity-dependent expression of immediate-early genes has …
and protein synthesis. While activity-dependent expression of immediate-early genes has …
Evolution of columns, modules, and domains in the neocortex of primates
JH Kaas - Proceedings of the National Academy of …, 2012 - National Acad Sciences
The specialized regions of neocortex of mammals, called areas, have been divided into
smaller functional units called minicolumns, columns, modules, and domains. Here we …
smaller functional units called minicolumns, columns, modules, and domains. Here we …
[HTML][HTML] Identification of visual cortex cell types and species differences using single-cell RNA sequencing
The primate neocortex exerts high cognitive ability and strong information processing
capacity. Here, we establish a single-cell RNA sequencing dataset of 133,454 macaque …
capacity. Here, we establish a single-cell RNA sequencing dataset of 133,454 macaque …
Evolution of Osteocrin as an activity-regulated factor in the primate brain
Sensory stimuli drive the maturation and function of the mammalian nervous system in part
through the activation of gene expression networks that regulate synapse development and …
through the activation of gene expression networks that regulate synapse development and …
[HTML][HTML] Uncovering molecular biomarkers that correlate cognitive decline with the changes of hippocampus' gene expression profiles in Alzheimer's disease
Background Alzheimer's disease (AD) is characterized by a neurodegenerative progression
that alters cognition. On a phenotypical level, cognition is evaluated by means of the …
that alters cognition. On a phenotypical level, cognition is evaluated by means of the …
Functional ultrasound imaging of deep visual cortex in awake nonhuman primates
Deep regions of the brain are not easily accessible to investigation at the mesoscale level in
awake animals or humans. We have recently developed a functional ultrasound (fUS) …
awake animals or humans. We have recently developed a functional ultrasound (fUS) …
[HTML][HTML] Five points on columns
KS Rockland - Frontiers in Neuroanatomy, 2010 - frontiersin.org
Abstract “Column,” like “gene,” has both conceptual and linguistic shortcomings. The simple
question “what is a column” is not easy to answer and the word itself is not easy to replace …
question “what is a column” is not easy to answer and the word itself is not easy to replace …
[HTML][HTML] Three counting methods agree on cell and neuron number in chimpanzee primary visual cortex
Determining the cellular composition of specific brain regions is crucial to our understanding
of the function of neurobiological systems. It is therefore useful to identify the extent to which …
of the function of neurobiological systems. It is therefore useful to identify the extent to which …
Evidence for cross-modal plasticity in adult mouse visual cortex following monocular enucleation
L Van Brussel, A Gerits, L Arckens - Cerebral Cortex, 2011 - academic.oup.com
The goal of this study was to assess cortical reorganization in the visual system of adult mice
in detail. A combination of deprivation of one eye and stimulation of the remaining eye …
in detail. A combination of deprivation of one eye and stimulation of the remaining eye …
Hippocampal c-Jun-N-terminal kinases serve as negative regulators of associative learning
In the adult mouse, signaling through c-Jun N-terminal kinases (JNKs) links exposure to
acute stress to various physiological responses. Inflammatory cytokines, brain injury and …
acute stress to various physiological responses. Inflammatory cytokines, brain injury and …