The introduction of the E Factor in 1992 focussed attention on the problem of waste
generation, defined as everything but the desired product, in chemicals manufacture and …

Biocatalysis has an enormous impact on chemical synthesis. The waves in which
biocatalysis has developed, and in doing so changed our perception of what organic …

Chiral amine diastereomers are ubiquitous in pharmaceuticals and agrochemicals, yet their
preparation often relies on low-efficiency multi-step synthesis. These valuable compounds …

Chiral amines are pivotal building blocks for the pharmaceutical industry. Asymmetric
reductive amination is one of the most efficient and atom economic methodologies for the …

Reductions play a key role in organic synthesis, producing chiral products with new
functionalities. Enzymes can catalyse such reactions with exquisite stereo‐, regio‐and …

Imine reductases catalyse the reductive amination of aldehydes or ketones with amines to
produce chiral amines—a key transformation in the preparation of fine chemicals and active …

Thermochemical conversion of fossil resources into fuels, chemicals, and materials has
rapidly increased atmospheric CO2 levels, hindering global efforts toward achieving carbon …

The synthesis of structurally diverse amines is of fundamental significance in the
pharmaceutical industry due to the ubiquitous presence of amine motifs in biologically active …

There is a dearth of research on how negative religious attitudes towards LGBTQ people
inform professional practice. This paper reports on a scoping review of 70 selected studies …

The synthesis of secondary and tertiary amines through the reductive amination of carbonyl
compounds is one of the most significant reactions in synthetic chemistry. Asymmetric …